阴虚证动物模型的建立方法及造模思路评析

发布时间：2018-01-12 00:31

本文关键词：阴虚证动物模型的建立方法及造模思路评析　出处：《中华中医药学刊》2017年03期 　论文类型：期刊论文

【摘要】：阴虚证是许多临床慢性病高发的中医证型,故建立模拟中医阴虚证相关证候的动物模型,对于探讨阴虚证的病理机制及提高中医药的临床疗效均有重要意义。通过查阅相关文献,根据中医阴虚证模型建立的指导思想和方法,将阴虚证的造模思路分为模拟阴虚证证候特点,模拟阴虚病因病机和模拟临床阴虚证高发病造模。对其造模思路和具体方法进行分析和比较,以期为建立更加科学、更加符合中医阴虚证特点的动物模型提供参考。
[Abstract]:Yin deficiency syndrome is a high incidence of many clinical chronic Chinese medicine syndrome type, so the establishment of simulation of TCM yin deficiency syndrome related syndromes animal model. It is of great significance to explore the pathological mechanism of yin deficiency syndrome and improve the clinical efficacy of traditional Chinese medicine. Through consulting relevant literature, according to the guiding ideology and method of establishing the model of yin deficiency syndrome of traditional Chinese medicine. The thinking of making model of yin deficiency syndrome is divided into three parts: simulating the characteristics of syndrome of yin deficiency, simulating the etiology and pathogenesis of yin deficiency and simulating the clinical model of high incidence of yin deficiency syndrome. The thinking and concrete methods of making model are analyzed and compared. In order to establish a more scientific, more in line with the characteristics of TCM Yin deficiency animal model to provide reference.
【作者单位】：浙江中医药大学第二临床医学院;杭州市西溪医院中西医结合病区;
【基金】：浙江省医药卫生科学研究基金项目(2012KYA158) 浙江省中医药科技计划项目(2014ZA089,2015ZA167) 杭州市科技发展计划项目(20120533Q11,20140733Q40)
【分类号】：R-332;R228
【正文快照】： 阴虚证是临床常见的多发病症之一,如慢性肝炎,肝硬化,糖尿病,肺癌中晚期,结核病和一些热病的中晚期等均表现为阴虚,故建立中医阴虚证的动物模型,对于研究中医药防治疾病,提高临床疗效及探讨阴虚证病理机制均都有重要意义。自1957年重庆医学院以甲状腺干粉喂饲家兔造成甲状腺功

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