调气通痹汤治疗局限性硬皮病的临床观察

发布时间：2018-01-14 17:13

本文关键词：调气通痹汤治疗局限性硬皮病的临床观察　出处：《黑龙江中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:探讨调气通痹汤治疗局限性硬皮病(气滞血瘀证)的临床疗效。方法:将符合标准的72例局限性硬皮病患者采取随机的方法,分为治疗组和对照组,两组均为36例。试验过程中治疗组、对照组各有1例脱落。治疗组给予调气通痹汤口服,对照组给予大黄蛰虫丸口服。4周为一个疗程,连续观察试验3个疗程。分别记录两组患者治疗前、治疗4周、治疗8周和治疗12周的皮损硬度积分,进行比较分析;记录两组患者治疗前后的生活质量情况,进行比较分析。结果:1.治疗4周时起,两组患者的皮损硬度积分与各自组内治疗前相比,均有显著性差异(P0.05);治疗8周时起至治疗12周末,两组间患者的皮损硬度积分相比较,存在显著性差异(P0.05);治疗12周末时,两组间患者的生活质量积分比较分析,存在显著性差异(P0.05);2.试验研究结束后,治疗组的总有效率为88.57%,对照组的总有效率为65.71%,两者总有效率对比,具有显著性差异(P0.05)。结论:1."调气通痹汤"能够明显降低局限性硬皮病(气滞血瘀证)患者皮损硬度积分;经"调气通痹汤"治疗后,患者的生活质量改善明显。2."调气通痹汤"是治疗局限性硬皮病(气滞血瘀证)安全有效的方剂。
[Abstract]:Objective: to investigate the clinical effect of Tiaoqi Tongbi decoction on local scleroderma (Qi stagnation and blood stasis syndrome). Methods: 72 patients with localized scleroderma were randomly divided into treatment group and control group. There were 36 cases in both groups. In the course of the experiment, one case fell off in the treatment group and one case in the control group. The treatment group was given Tiaoqi Tongbi decoction orally, and the control group was given rhubarb stinging pill for 4 weeks as a course of treatment. The hardness scores of the two groups were recorded before, 4 weeks, 8 weeks and 12 weeks, respectively. The quality of life (QOL) of the two groups was recorded and compared before and after treatment. Results: 1. After 4 weeks of treatment, the hardness scores of skin lesions in the two groups were compared with those before treatment in their respective groups. There was significant difference between the two groups (P 0.05). From 8 weeks to 12 weeks of treatment, there was a significant difference between the two groups in the score of skin lesion hardness (P 0.05). At the end of 12 weeks, there was a significant difference in quality of life score between the two groups (P 0.05). 2. After the trial, the total effective rate of the treatment group was 88.57 and the total effective rate of the control group was 65.71. The total effective rate of the treatment group was 88.57 and the total effective rate of the control group was 65.71. Conclusion: 1. "Tiaoqi Tongbi decoction" can significantly reduce the hardness integral of skin lesions in patients with localized scleroderma (qi stagnation and blood stasis syndrome). After the treatment of "Tiaoqi Tongbi decoction", the quality of life of the patients improved obviously. 2. "Tiaoqi Tongbi decoction" is a safe and effective prescription for the treatment of localized scleroderma (qi stagnation and blood stasis syndrome).
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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