通便方治疗慢传输型便秘阴虚肠燥证临床观察

发布时间：2018-01-15 03:22

本文关键词：通便方治疗慢传输型便秘阴虚肠燥证临床观察　出处：《湖南中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:探讨通便方治疗慢传输型便秘阴虚肠燥证的临床疗效和安全性。方法:本研究采取完全随机设计的方法。收集来自于湖南省中医附一72例符合STC诊断标准的志愿者,采用随机数字表法分为治疗组和对照组。完成观察的治疗组和对照组各30例,其中治疗组予通便方联合一般治疗;对照组予莫沙必利片联合一般治疗。观察4周,对患者临床疗效、中医证候积分、结肠传输试验、持续稳定性指标、安全性指标进行统计分析。结果:1、治疗28天后,治疗组的总有效率为90%,对照组的总有效率为73.33%,两组总有效率比较差异有统计学意义(P0.05)。2、在中医证候总积分方面,两组自身前后证候总积分比较差异有统计学意义(P0.05),治疗后治疗组与对照组比较差异有统计学意义(P0.05)。3、在主症积分比较方面,两组各项自身前后比较差异有统计学意义(P0.05),治疗后治疗组和对照组比较差异差异有统计学意义(P0.05)。4、在次症积分比较方面,两组自身前后比较,治疗组差异有统计学意义(P0.05),对照组在失眠方面治疗前后差异有统计学意义(P0.05),治疗后两组比较差异均有统计学意义(P0.05)。5、在钡剂残余数方面,两组自身前后比较差异有统计学意义(P0.05),治疗后两组比较差异有统计学意义(P0.05)。6、在持续稳定性评价方面,两组复发率比较差异无统计学意义(P0.05)。7、在不良方应方面,对照组出现1例不良反应,治疗组未出现不良反应。结论:通便方配合一般治疗能有效治疗慢传输型便秘阴虚肠燥证患者,明显改善中医症状,安全无毒副作用,值得临床推广。
[Abstract]:Objective: to investigate the clinical efficacy and safety of Tongbian recipe in treating chronic constipation with Yin deficiency and intestinal dryness. In this study, a totally randomized design was used to collect 72 volunteers from Hunan Province who met the diagnostic criteria of STC. The treatment group and control group were divided into treatment group and control group with 30 cases in each group, in which the treatment group was treated with Tongbian recipe combined with general treatment. The control group was treated with mosapride tablet combined with general treatment. After 4 weeks of observation, the clinical efficacy, TCM syndrome score, colonic transit test, sustained stability index and safety index were statistically analyzed. Results: 1. After 28 days of treatment, the total effective rate of the treatment group was 90 and the total effective rate of the control group was 73.33. The difference of the total effective rate between the two groups was statistically significant (P 0.05). In the total integral of TCM syndromes, the two groups before and after the comparison of the total syndromes integral difference was statistically significant, the treatment group and the control group after the difference was statistically significant (P 0.05). In the main symptom score comparison, there was significant difference between the two groups before and after the comparison, the treatment group and the control group after treatment, the difference was statistically significant (P 0.05). In terms of score comparison, the two groups before and after the comparison, the treatment group difference was statistically significant, the control group in insomnia before and after treatment has statistical significance (P0.05). After treatment, the difference between the two groups was statistically significant (P 0.05). In the barium residue, the difference between the two groups before and after the comparison was statistically significant (P 0.05). After treatment, the difference between the two groups was statistically significant (P 0.05). In the evaluation of the stability of the two groups, there was no significant difference in the recurrence rate between the two groups (P 0.05), and there was no significant difference in the recurrence rate between the two groups (P 0.05). Conclusion: Tongbian recipe combined with general treatment can effectively treat chronic constipation patients with Yin deficiency and intestinal dryness syndrome, and obviously improve the symptoms of TCM. Safety and no side effects, worthy of clinical promotion.
【学位授予单位】：湖南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R256.35

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