玉屏风颗粒对复发性生殖器疱疹患者血清IFN-γ、IL-4水平的影响研究

发布时间：2018-01-15 07:27

本文关键词：玉屏风颗粒对复发性生殖器疱疹患者血清IFN-γ、IL-4水平的影响研究　出处：《中国性科学》2017年04期 　论文类型：期刊论文

【摘要】：目的:研究玉屏风颗粒对复发性生殖器疱疹患者血清干扰素-γ(IFN-γ)、白细胞介素-4(IL-4)水平的影响。方法:选取从2015年1月至2016年1月在我院就诊的100例复发性生殖器疱疹患者,将所有患者随机均分为治疗组1和治疗组2(各50例),其中治疗组1口服泛昔洛韦片,治疗组2冲服玉屏风颗粒,并从门诊体检处选取50例正常人群作为正常组,对比治疗组1、治疗组2治疗前后血清IFN-γ、IL-4水平。结果:两治疗组患者在治疗前后血清IFN-γ、IL-4水平均有明显的变化,差异具有统计学意义(P0.05);治疗组2治疗前后的变化明显大于治疗组1,差异具有统计学意义(P0.05)。结论:玉屏风颗粒在治疗复发性生殖器疱疹患者过程中能明显升高血清IFN-γ、降低IL-4水平。
[Abstract]:Objective: to study the effect of Yupingfeng granule on serum interferon- 纬 (IFN- 纬) in patients with recurrent genital herpes. Methods: from January 2015 to January 2016, 100 patients with recurrent genital herpes were selected. All patients were randomly divided into treatment group 1 and treatment group 2 (50 cases each), treatment group 1 oral panciclovir, treatment group 2 take Yuping Feng granule. At the same time, 50 normal people were selected as normal group from the outpatient physical examination, compared with treatment group 1, treatment group 2 before and after treatment of serum IFN- 纬. Results: before and after treatment, the serum levels of IFN- 纬 and IL-4 were significantly changed in the two groups, and the difference was statistically significant (P 0.05). The changes before and after treatment in treatment group 2 were significantly larger than those in treatment group 1. Conclusion: Yupingfeng granule can increase serum IFN- 纬 and decrease the level of IL-4 during the treatment of recurrent genital herpes.
【作者单位】：海南医学院第二附属医院皮肤科;荆州市中心医院皮肤科;十堰市妇幼保健院产科;
【分类号】：R275.9
【正文快照】： 2荆州市中心医院皮肤科,湖北荆州4340203十堰市妇幼保健院产科,湖北十堰442000生殖器疱疹(genital herpes,GH)由单纯疱疹病毒感染生殖器部位皮肤黏膜引起,该病毒潜伏于骶神经根区,激活后于泌尿生殖器、肛周皮肤黏膜处产生水疱、炎症、溃疡等病症[1,2]。机体感染单纯疱疹病毒引

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