温阳活血法内外同治阳虚血瘀型不稳定型心绞痛70例临床观察

发布时间：2018-01-15 15:27

本文关键词：温阳活血法内外同治阳虚血瘀型不稳定型心绞痛70例临床观察　出处：《中医杂志》2017年19期 　论文类型：期刊论文

【摘要】：目的观察温阳活血法内外同治阳虚血瘀型不稳定型心绞痛的临床疗效和安全性。方法将140例不稳定型心绞痛患者随机分为治疗组与对照组各70例。两组均给予常规西药和口服定痛救心汤,对照组另加外用穴位空白贴,治疗组另加外用穴位贴敷心痛膏,两组均连续治疗14天。观察治疗前后两组主要临床症状、心电图、中医证候积分、硝酸甘油停减情况以及血脂[包括血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)]和左室射血分数(LVEF)改善情况及不良反应。两组均随访6个月。结果治疗组主要临床症状和心电图疗效总有效率分别为84.3%和77.1%,明显优于对照组的68.6%和64.3%(P0.05)。治疗后两组中医证候积分均较治疗前降低,并且治疗组较对照组降低更明显(P0.05或P0.01)。治疗后治疗组硝酸甘油停减率为80.0%,高于对照组的65.7%(P0.05)。两组TC、TG、LDL-C水平均较治疗前降低,HDL-C水平较治疗前上升(P0.05或P0.01),治疗组优于对照组(P0.05)。治疗组治疗后LVEF明显高于对照组(P0.05)。两组均无明显不良反应发生。治疗组心脏不良事件的发生率低于对照组(P0.05)。结论温阳活血法内外同治阳虚血瘀型不稳定型心绞痛临床效果肯定,无明显不良反应。
[Abstract]:Objective to observe the clinical efficacy and safety of warming yang and activating blood circulation method in treating unstable angina pectoris with deficiency of yang and blood stasis. Methods 140 patients with unstable angina pectoris were randomly divided into treatment group and control group. Routine western medicine and oral Dingtong Jiuxin decoction were given. The control group was treated with external acupoint blank paste, the treatment group with external acupoint application of Xintong ointment, the two groups were treated continuously for 14 days. The main clinical symptoms, electrocardiogram and TCM syndromes were observed before and after treatment. Stopping and decreasing of nitroglycerin and blood lipids. [These include serum total cholesterol (TC), triglyceride (TG), and high density lipoprotein cholesterol (HDL-C). Low density lipoprotein cholesterol (LDL-C) and left ventricular ejection fraction (LVEF). The two groups were followed up for 6 months. Results the total effective rates of main clinical symptoms and electrocardiogram in the treatment group were 84.3% and 77.1% respectively. Significantly better than the control group (68.6% and 64.3). After treatment, the TCM syndromes scores of the two groups were lower than those before treatment. And the treatment group than the control group decreased more significantly P 0.05 or P 0.01. After treatment the treatment group nitroglycerin stop reduction rate is 80.0%. Compared with the control group (65.7%), the LDL-C level of the two groups was lower than that of the control group (P0.05 or P0.01). The LVEF of the treatment group was significantly higher than that of the control group (P 0.05). The incidence of adverse cardiac events in the treatment group was lower than that in the control group (P 0.05). Conclusion the clinical effect of warming yang and activating blood circulation method in treating unstable angina pectoris with deficiency of yang and blood stasis is positive. There was no obvious adverse reaction.
【作者单位】：天津市中医药研究院附属医院;
【基金】：天津市中医药研究院附属医院中医中西医结合科研课题(2015YN015)
【分类号】：R259
【正文快照】： 不稳定型心绞痛是严重威胁人类健康的临床常见疾病之一。近年来随着社会生活方式及饮食结构的改变,其发病率逐年增加且发病年龄呈现年轻化。现代医学治疗不稳定型心绞痛主要采用抗血小板聚集、扩张冠状动脉、调节血脂、β受体阻滞剂、抗凝等药物治疗或冠状动脉支架植入术、冠

【相似文献】