不同证型功能性消化不良患者胃容受性及胃排空功能差异的临床研究

发布时间：2018-01-15 20:17

本文关键词：不同证型功能性消化不良患者胃容受性及胃排空功能差异的临床研究　出处：《南京中医药大学学报》2017年06期 　论文类型：期刊论文

【摘要】：目的通过液体营养餐负荷实验结合B超检查,探讨分析不同证型功能性消化不良(FD)患者胃容受性舒张及排空功能的差异。方法入选74例研究对象,健康者14例(HS组),FD患者60例(脾虚气滞型33例,脾虚湿阻型16例,脾阳虚型11例)。所有研究对象均进行液体营养餐负荷实验,结合VAS视觉评分,记录阈值和最大饮入量;并且通过超声测量,比较不同证型的胃排空率及半排空时间。结果 FD组3种证型最大饮入量均低于HS组(P0.05~0.01),脾虚湿阻型最大饮入量低于脾虚气滞、脾阳虚型(P0.05);FD组3种证型与HS组比较,脾阳虚型餐后90min远端胃排空率低于HS组(P0.05);脾虚湿阻型远端胃半排空时间较HS组、脾虚气滞型和脾阳虚型均延长(P0.05)。结论不同证型FD患者胃肠运动功能有差异,辨证为脾虚湿阻型患者减退更显著,为中医辨证施治提供理论依据。
[Abstract]:Objective to analyze the difference of gastric receptive diastolic and emptying function in patients with different types of functional dyspepsia (FDD) by liquid meal loading test combined with B-ultrasonography. Methods 74 patients were included in the study. There were 60 patients with FD in HS group (spleen deficiency qi stagnation type 33 cases spleen deficiency dampness obstruction type 16 cases spleen yang deficiency type 11 cases). Combined with VAS visual score, the threshold and the maximum intake were recorded. The gastric emptying rate and half emptying time of different syndromes were compared by ultrasonic measurement. Results the maximum intake of the three syndrome types in FD group was lower than that in HS group (P 0.05 / 0.01). The maximum intake of spleen deficiency dampness obstruction type was lower than that of spleen deficiency qi stagnation, and spleen yang deficiency type was P0.05A; Compared with HS group, the distal gastric emptying rate of FD group 90 min after meal was lower than that of HS group (P 0.05). The half-emptying time of distal stomach of spleen deficiency dampness obstruction type was longer than that of HS group, spleen deficiency qi stagnation type and spleen yang deficiency type prolonged P0.050.Conclusion there are differences in gastrointestinal motility in FD patients with different syndromes. Differentiation of symptoms and signs for spleen deficiency dampness block type patients decreased more significantly, for TCM syndrome differentiation and treatment to provide theoretical basis.
【作者单位】：武汉市中西医结合医院消化内科;湖北中医药大学第一临床医学院;
【基金】：国家重点基础研究发展项目(“973”计划)(2013CB531703)
【分类号】：R259
【正文快照】： 功能性消化不良(FD)是指由胃、十二指肠功能紊乱所引起的以上腹部隐痛、餐后饱胀、早饱、烧心等为主要临床表现的功能性胃肠病,同时需排除引起上述症状的器质性或代谢性疾病。根据罗马Ⅲ分型标准,FD分为上腹痛综合征(EPS)和餐后不适综合征(PDS)。本研究针对PDS进行讨论。为探

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