寒凝血瘀型家兔模型的实验观察

发布时间：2018-01-16 04:17

  本文关键词：寒凝血瘀型家兔模型的实验观察　出处：《辽宁中医杂志》2017年09期 　论文类型：期刊论文

  更多相关文章： 寒凝血瘀 家兔模型 实验观察

【摘要】：目的:建立寒凝血瘀型家兔模型。方法:采用冰冷刺激的方法复制寒凝血瘀家兔模型,将20只家兔按体重随机分为(1)空白对照组,(2)模型一组,(3)模型二组,(4)模型三组,(5)模型四组,每组4只,采用体征观察、微循环观测、血液流变学检测、凝血象检测评价寒凝血瘀家兔模型的可靠性。结果:造模后,模型组(共4组)家兔与空白组家兔相比,精神欠佳,饮食及饮水量减少,二便稀少,耳朵和眼睛的微血管屈曲有分叉,血液中的全血还原黏度和全血黏度增加,纤维蛋白原有所升高。结论:上述方法建立的寒凝血瘀家兔模型符合中医证候特点和现代医学病理生理学基础,具有一定的理论和实践意义。
[Abstract]:Objective: to establish a rabbit model of cold coagulation and blood stasis. Methods: 20 rabbits with cold coagulation and blood stasis were randomly divided into 2 groups according to their body weight. (3) Model group 2: 4) Model group 3: 5) Model group, 4 rats in each group, physical sign observation, microcirculation observation and hemorheology test were used. Results: after the establishment of the model, compared with the blank group, the model group (4 groups) had poor mental state, reduced diet and drinking water, and scarce stool. The microvascular flexion of the ears and eyes has a bifurcation, and the whole blood reduction viscosity and the whole blood viscosity in the blood increase. Conclusion: the rabbit model of cold coagulation and blood stasis established by the above method accords with the characteristics of TCM syndromes and the pathophysiology of modern medicine and has certain theoretical and practical significance.
【作者单位】： 天津中医药大学;天津市滨海新区大沽社区卫生服务中心;天津市第四中心医院;烟台凤凰山医院;天津中医药大学针灸推拿学院;
【基金】：国家自然科学基金项目(81273673)
【分类号】：R228;R-332
【正文快照】： 血瘀证是一个与血液循环障碍相关的病理过程,主要表现在血流变的异常、微循环障碍和局部血流动力学异常等方面。中医理论认为,寒为阴邪,具有凝滞、收引的特性。血脉受寒则凝,日久则瘀。本实验拟采用冰冷刺激大鼠造模,通过观察大鼠冰冷刺激前后症状体征变化、眼睛和耳朵微循环，

本文编号：1431509