麦粒灸治疗非小细胞肺癌患者呼吸系统症状的临床观察

发布时间：2018-01-16 17:23

本文关键词：麦粒灸治疗非小细胞肺癌患者呼吸系统症状的临床观察　出处：《南京中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：客观评价麦粒灸治疗不同证型的非小细胞肺癌的患者受益情况及安全可行性,为麦粒灸在非小细胞肺癌的治疗和应用中提供临床参考。方法：将2015年4月至2016年3月就诊于南京鼓楼医院呼吸科、中医科,符合纳入标准的非小细胞肺癌病例进行辨证分型,并按照分层随机抽样法将患者分为麦粒灸组与对照组各32例,每组均予必要的对症支持治疗及2种常用中成药扶正抗癌。麦粒灸组在此基础上施以麦粒灸,每日一次,每穴7壮,14次为1疗程,对照组不予麦粒灸。观察两组治疗前后患者的呼吸系统临床症状积分、KPS评分、不良事件等。结果：1麦粒灸组与对照组组间比较：1)麦粒灸组治疗后有效率为86.67%,高于对照组的63.33%,差异有统计学意义(P0.05)。2)麦粒灸组对咳嗽、咯痰、胸闷、胸痛、气喘等呼吸道症状改善,较对照组差异显著(P0.05),而对痰血改善不明显。3)麦粒灸组较对照组KPS评分升高明显(P0.05)。4)两组均未出现严重不良事件,发生率无统计。2.麦粒灸组两证型比较：1)麦粒灸组脾虚痰湿证治疗有效率为92.85%,气阴两虚证治疗有效率为81.25%,差异无统计学意义(P0.05)。2)治疗后麦粒灸组脾虚痰湿证的咳嗽、咯痰症状的改善优于气阴两虚证(P0.05),余呼吸系统症状积分及KPS评分改善无统计学差异。结论：在中医扶正抗癌及必要对症支持治疗的基础上,麦粒灸能更好的改善非小细胞肺癌患者的呼吸系统症状,尤其是患者的咳嗽、咯痰、胸闷、胸痛、气喘等症状。经麦粒灸治疗后脾虚痰湿型患者的咳嗽、咯痰症状改善更显著。麦粒灸在非小细胞肺癌的治疗中安全有效,值得临床推广。
[Abstract]:Objective: to evaluate the benefit and safety of granulated moxibustion in the treatment of non-small cell lung cancer (NSCLC) with different syndromes. To provide clinical reference for the treatment and application of granulated moxibustion in non-small cell lung cancer. Methods: from April 2015 to March 2016, we visited the Department of Respiratory Medicine, Department of traditional Chinese Medicine, Nanjing Gulou Hospital. According to the inclusion criteria, the patients with non-small cell lung cancer were divided into two groups: moxibustion group (n = 32) and control group (n = 32) according to stratified random sampling. Each group was given necessary symptomatic support therapy and 2 common traditional Chinese medicine to strengthen the anticancer. The granulated moxibustion group was treated with grain moxibustion once a day and 14 times per acupoint for a course of treatment. The patients in the control group were treated with moxibustion without granulation. The clinical symptoms of respiratory system and KPS score were observed before and after treatment in the two groups. Results compared with the control group, the effective rate of the grain moxibustion group was 86.67, which was higher than that of the control group (63.33%). The difference was statistically significant (P0.05. 2) the improvement of respiratory symptoms such as cough, sputum, chest tightness, chest pain and asthma in the moxibustion group was significantly higher than that in the control group (P 0.05). However, the improvement of phlegm and blood was not obvious. 3) the KPS score of the moxibustion group was significantly higher than that of the control group (P0.05. 4) there were no serious adverse events in both groups. The incidence rate was not statistically .2.Compared with the two syndrome types of grain moxibustion group, the effective rate of spleen deficiency and phlegm dampness syndrome in grain moxibustion group was 92.85 and that of qi and yin deficiency syndrome was 81.25%. The difference was not statistically significant (P0.05N. 2) after treatment, the cough and expectoration symptoms of spleen deficiency and phlegm dampness syndrome in wheat grain moxibustion group were better than those of Qi and Yin deficiency syndrome (P0.05). There was no significant difference in the score of residual respiratory system symptoms and the improvement of KPS score. Conclusion: on the basis of traditional Chinese Medicine (TCM) for cancer prevention and necessary treatment of symptomatic support. Grain moxibustion can improve the respiratory symptoms of non-small cell lung cancer patients, especially the cough, sputum, chest tightness, chest pain, asthma and other symptoms. Grain moxibustion is safe and effective in the treatment of non-small cell lung cancer.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.5

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