湿疹洗剂方治疗婴儿湿疹的临床疗效研究

发布时间：2018-01-19 01:18

本文关键词： 湿疹洗剂疗效观察婴儿湿疹皮损表面菌　出处：《辽宁中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:本研究通过随机对照临床试验,对湿疹洗剂治疗婴儿湿疹的临床疗效的改善情况作出评价,予以明确临床实用价值。材料与方法:随机表法把61例患者随机分为治疗组及对照组,其中治疗组31例,对照组30例。治疗组外用湿疹洗剂治疗,皮损仅有红斑、丘疹、干燥脱屑者,予以温洗后,外用婴儿保湿剂;如皮损有糜烂、渗出、结痂者,湿敷于皮损部位,面部以冷敷为主,湿敷后外涂紫黄油膏,每次15min,每日2次,疗程为14±2天。对照组:采用皮炎洗剂,皮损仅有红斑、丘疹、干燥脱屑者,予以温洗后,外用婴儿保湿剂;如皮损有糜烂、渗出、结痂者,湿敷患处,湿敷后外涂氧化锌油,每次15min,每日2次,疗程为14±2天。运用统计学方法对疗效、皮损形态、瘙痒程度、皮损面积、临床症状总积分、皮肤表面细菌检出情况等进行分析。结果:1.临床观察显示,患者皮损治疗组症状评分的总有效率为93.33%,对照组总有效率为63.33%,经秩和检验,P0.05,表明治疗组疗效优于对照组。2.两组皮损面积、皮损形态、瘙痒程度治疗后积分比较,经秩和检验,P0.05,表明治疗组疗效均优于对照组。3.治疗组西医临床分型渗出型婴儿湿疹的有效率为94.44%,干燥型婴儿湿疹的有效率为91.6%,经秩和检验,P0.05,表明湿疹洗剂治疗渗出型婴儿湿疹与干燥型疗效无明显差异。4.治疗组中医辨证分型胎毒湿热型有效率为94.18%,脾虚湿蕴型有效率为92.31%,经秩和检验,P0.05,表明湿疹洗剂治疗胎毒湿热型婴儿湿疹与脾虚湿蕴型疗效无明显差异。5.治疗组前后组内皮损表面菌检出率明显下降,表明湿疹洗剂具有显著的杀菌疗效,治疗后两组皮损表面菌的检出率为治疗组6.67%和对照组16.67%,经秩和检验,P0.05,治疗组与对照组无明显差异。结论:1.湿疹洗剂治疗婴儿湿疹优于对照组。2.湿疹洗剂治疗渗出型婴儿湿疹与干燥型疗效无明显差异。3.湿疹洗剂治疗胎毒湿热型婴儿湿疹与脾虚湿蕴型疗效无明显差异。4.湿疹洗剂有很强的杀菌作用。
[Abstract]:Objective: to evaluate the effect of eczema lotion on infant eczema by randomized controlled clinical trial. Materials and methods: 61 patients were randomly divided into treatment group (31 cases) and control group (30 cases). Skin lesions only erythema, papules, dry detritus, warm wash, external use of baby moisturizer; If the skin lesions have erosion, exudation, scab, wet application in the lesions, the face with cold compress, wet application of purple yellow ointment, 15 minutes, twice a day. The course of treatment was 14 卤2 days. The control group was treated with dermatitis lotion. The skin lesions were only erythema, papules, dry and desquamated. If the skin lesions have erosion, exudation, scab, wet application, wet application of zinc oxide oil, 15 minutes each time, twice a day, the course of treatment is 14 卤2 days. The degree of pruritus, the area of skin lesion, the total score of clinical symptoms and the detection of bacteria on skin surface were analyzed. Results: 1. Clinical observation showed that the total effective rate of symptom score of patients with skin lesion treatment group was 93.33%. The total effective rate of the control group was 63.33 and the rank sum test showed that the curative effect of the treatment group was better than that of the control group. The rank sum test showed that the curative effect of the treatment group was better than that of the control group. The effective rate of eczema in the treatment group was 94.44%. The effective rate of dry type infant eczema was 91.6%, which was tested by rank sum test (P0.05). The results showed that there was no significant difference between eczema lotion and dry type. 4. The effective rate of TCM syndrome differentiation was 94.18 in the treatment group and 92.31% in the spleen deficiency dampness accumulation type. The results of rank sum test showed that there was no significant difference in the efficacy of eczema lotion in treating infant eczema with fetotoxic damp-heat type and spleen deficiency and dampness accumulation type. 5. The positive rate of surface bacteria in skin lesions in the treatment group decreased significantly before and after treatment. The results showed that eczema lotion had significant bactericidal efficacy. After treatment, the detection rate of surface bacteria in the two groups was 6.67% in the treatment group and 16.67in the control group, with rank sum test (P0.05). There was no significant difference between the treatment group and the control group. 1. Eczema lotion is superior to control group in treatment of infant eczema. There is no significant difference between eczema lotion and dry type. There is no obvious difference. 4. Eczema lotion has a strong bactericidal effect.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R275.9

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