前列通瘀胶囊治疗慢性前列腺炎Meta分析

发布时间：2018-01-19 18:27

本文关键词： 前列通瘀胶囊慢性前列腺炎 Meta分析系统评价　出处：《现代医院》2017年03期 　论文类型：期刊论文

【摘要】：目的评价前列通瘀胶囊治疗慢性前列腺炎(Chronic Prostatitis,CP)的临床疗效。方法计算机检索中国知识资源总库、中国生物医学文献数据库、万方数据库,收集前列通瘀胶囊治疗CP的随机对照临床试验或半随机对照临床试验,检索时限均从建库至2016年1月,对纳入研究的方法学质量进行评价,用Rev Man 5.3软件进行统计分析。结果 Meta分析结果显示:前列通瘀胶囊单用或联用其他药物治疗CP在治愈率[OR=1.96,95%CI(1.63,2.34),P0.05]、总有效率[OR=2.85,95%CI(2.27,3.59),P0.05]、症状积分指数(NIH-CPSI)[MD=-4.92,95%CI(-9.65,-0.18),P0.05]均显著优于对照组,差异有统计学意义,但前列腺液白细胞计数(EPSWBC)[MD=-1.92,95%CI(-3.91,0.06),P0.05]、不良反应[OR=0.97,95%CI(0.59,1.60,P0.05)]差异无统计学意义。结论本Meta分析表明前列通瘀胶囊单用或联用其他药物治疗CP,应用安全,在治愈率、总有效率及改善NIH-CPSI上优于对照组,对前列腺液白细胞计数的影响及副作用与对照组相当。
[Abstract]:Objective to evaluate the clinical efficacy of Qianliesong Yu capsule in the treatment of chronic prostatitis. Chinese biomedical literature database, Wanfang database, collected Qianliantongyu capsule for CP randomized controlled clinical trial or semi-randomized controlled clinical trial, the retrieval time from the establishment of the database to January 2016. Evaluation of the quality of methodologies included in the study. Results the results of Meta analysis showed that the cure rate of CP treated with Qianliesong Tongyu capsule alone or with other drugs was higher than that of the control group. [OR1. 96 / 95 CIQ / 1.63 / 2.34 / (P0.05), total effective rate. [ORO 2.85 / 95 CIQ 2.27 / 3.59 (P0.05), symptom score index (NIH-CPSII). [MD-4.92 ~ 95% CIQ -9.65% -0.18% (P0.05) was significantly better than the control group (P < 0.05), the difference was statistically significant, but the prostatic fluid white blood cell count (EPSWBC) was significantly higher than that in the control group (P < 0.05). [MD-1.92% 95% CIQ -3.91% 0.06% (P0.05), adverse reactions. [OR0.97 / 95 / CI0.59 / 1.60. Conclusion this Meta analysis shows that Qianliesong Yu capsule alone or in combination with other drugs in the treatment of CPP is safe in the cure rate. The total effective rate and the improvement of NIH-CPSI were superior to those in the control group, and the effect and side effects on the leukocyte count in the prostatic fluid were similar to those in the control group.
【作者单位】：广州中医药大学第一临床医学院;
【分类号】：R277.5
【正文快照】： 慢性前列腺炎(Chronic Prostatitis,CP)是成年男性的常见病之一,虽然不是一种直接威胁生命的疾病,但严重影响患者的生活质量。CP严重危害男性健康,患病率高达46.63%[1],CP是以尿频、尿急、排尿不尽、尿道灼热等排尿异常症状,会阴、下腹部、腰骶部及睾丸等部位疼痛不适为主要症

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