理中复元方结合针刺法治疗脾虚痰瘀型慢性萎缩性胃炎

发布时间：2018-01-21 09:49

本文关键词： 理中复元方针刺慢性萎缩性胃炎脾虚痰瘀型临床观察　出处：《中成药》2017年09期 　论文类型：期刊论文

【摘要】：目的通过随机、平行对照试验观察理中复元方(黄芪、白术、茯苓,等)结合针刺法(胃俞、中脘、内关、足三里)对脾虚痰瘀型慢性萎缩性胃炎的疗效。方法 108例患者随机均分为理中复元方结合针刺组、理中复元方组和对照组(叶酸),4个月为一疗程。观察3组治疗前后的临床主症、体征,比较胃镜分析、理化检查。结果各组胃黏膜颜色和活动性有显著差异,中医症候积分治疗前后也有显著差异。在症状疗效方面,各组有显著差异;在病理疗效、免疫组化和综合疗效方面,组间差异无统计学意义,理中复元方结合针刺组总有效率为42%,理中复元方治疗组总有效率为36.5%,对照组总有效率为24.1%。方差分析和秩和检验显示,两组间差异有统计学意义。结论理中复元方结合针刺可优化对脾虚痰瘀型慢性萎缩性胃炎的疗效。
[Abstract]:Objective to observe the combination of Li Zhong Fu Yuan Fang (Astragalus membranaceus, Atractylodes macrocephala, Poria cocos, etc.) with acupuncture (Weishu, Zhongwan, Neiguan) in a randomized, parallel controlled trial. Methods 108 cases of chronic atrophic gastritis with spleen deficiency and phlegm stasis were randomly divided into three groups: Lizhong Fuyuan prescription combined with acupuncture group, Lizhong Fuyuan prescription group and control group (folic acid). Four months as a course of treatment. Observed before and after treatment of the main clinical symptoms, signs, comparative gastroscopy analysis, physical and chemical examination. Results there were significant differences in the color and activity of gastric mucosa in each group. There were significant differences before and after TCM symptom integral treatment. In the pathological effect, immunohistochemistry and comprehensive efficacy, there was no statistical difference between the two groups. The total effective rate of the combination of Li Zhong Fu Yuan Fang and acupuncture group was 42. The total effective rate of the treatment group was 36.5%. The total effective rate of the control group was 24.1.The variance analysis and rank sum test showed that the difference between the two groups was statistically significant. Conclusion Lizhong Fuyuan prescription combined with acupuncture can optimize the therapeutic effect on chronic atrophic gastritis with spleen deficiency and phlegm stasis type.
【作者单位】：上海中医药大学附属市中医医院;复旦大学附属华东医院;
【基金】：上海市科学技术委员会课题项目(14401933000)
【分类号】：R259
【正文快照】： 近年来,中国社会老龄化趋势越来越严重,人们对腌制、速冻、富含防腐剂食品的喜爱,导致慢性萎缩性胃炎的发病率也逐年上升。本研究对3年来108例诊断为慢性萎缩性胃炎、幽门螺杆菌检测呈阴性的患者进行了临床观察,并取得了显著的疗效,现报告如下。1临床资料1.1纳入标准1.1.1纳入

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