太阴调胃汤加减治疗慢性胃炎的临床研究

发布时间：2018-01-22 01:04

  本文关键词： 太阴调胃汤加减 慢性胃炎 临床研究　出处：《延边大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:通过观察朝医太阴人方剂太阴调胃汤加减对太阴人慢性胃炎的朝医临床疗效,为该方药的临床应用提供更可靠的理论依据。方法:将2016年1月至2016年12月期间,在延边朝医医院和延边中医医院门诊及疗区就诊收治的太阴人慢性胃炎的患者,随机分为治疗组30例和对照组各30例。两组患者在性别、病程、病情、年岁上均无显著性差异,(P0.05),具有可比性。治疗组用太阴调胃汤加减汤剂(桔梗10g,薏苡仁15g,莱菔子10g,干栗15g,五味子5g,石菖蒲5g,白及10g,蚕砂10g麦门冬5g,)治疗。用自动煎药机水煎太阴调胃汤加减,真空袋包装,每袋200ml,一次1袋,日2次口服。对照组用常规的西药三联治疗方法:(1)泮托拉唑注射液60ml+生理盐水250ml,每日1次,静脉滴注。(2)阿莫西林片1g,每日2次,口服;克拉霉素片0.25mg,每日2次,口服。7天为1个疗程,观察2个疗程。主要观察两组治疗后的疗效、两组治疗前后朝医证候积分、两组胃镜检查结果、两组治疗前后病理检查结果、两组治疗前后HP检查结果、安全性指标观察等。结果:两组在给予药物治疗14天后,临床效果比较显示:治疗组总有效率显然明显比对照组高,有显著的差异(P0.05),具有统计学意义;两组治疗前,治疗后的朝医证候积分的比较示:治疗组有效率明显高于对照组,有显著性差异(P0.05),有统计学意义;两组胃镜检查结果显示:治疗组有效率明显高于对照组;两组治疗前后病理检查结果比较示:治疗组很显然明显优于对照组,有显著性差异(P0.05),有统计学意义;治疗组和对照组,治疗前后HP检查结果的比较示:治疗组明显优于对照组,有显著性差异(P0.05),有统计学意义;安全性指标观察两组患者治疗前后生命体征、血常规、尿常规、便常规、肝功能(ALT、AST)、肾功能(BUN、Cr、UA)及心电图均正常。此外,在临床观察过程当中,治疗与对照两组,均未发现不良反应。结论:研究结果表明,朝医方太阴调胃汤加减能有效的改善太阴人慢性胃炎的临床症状,具有一定程度的胃粘膜修复作用。
[Abstract]:Objective: to observe the clinical effect of Taiyin Tiaowei decoction on chronic gastritis of Taiyin. To provide a more reliable theoretical basis for the clinical application of the prescription. Methods: from January 2016 to December 2016. The patients with chronic gastritis of Taiyin were randomly divided into treatment group (n = 30) and control group (n = 30). The treatment group was treated with Taiyin Tiaowei decoction (10g of Platycodon, 15g of Coix seed, 10g of semen Raphani, 15g of dried Chestnut). Treatment of Schisandra chinensis 5g, Acorus calamus 5g, white and 10g, silkworm sand 10g. Decoction of Taiyin and stomach with automatic decoction machine, vacuum bag packing, 200 ml per bag, 1 bag once. The control group was treated with routine western medicine treatment method: 1) pam Tora injection 60ml normal saline 250ml, once a day, iv. 2) amoxicillin tablet 1g. 2 times a day, orally; Clarithromycin tablets 0.25 mg, twice a day, oral 7 days as a course of treatment, observe two courses of treatment. The main observation of the two groups after treatment, the two groups before and after treatment before and after the integration of the Korean medical syndrome, the results of two groups of gastroscopy. The results of pathological examination before and after treatment, the results of HP examination before and after treatment in both groups, the observation of safety indexes, etc. Results: after 14 days of drug therapy, the two groups were treated with drugs. The comparison of clinical results showed that the total effective rate of the treatment group was obviously higher than that of the control group, and there was a significant difference between the treatment group and the control group (P 0.05). The comparison of syndrome score before and after treatment in the two groups showed that the effective rate in the treatment group was significantly higher than that in the control group with significant difference (P 0.05). The results of gastroscopy in the two groups showed that the effective rate of the treatment group was significantly higher than that of the control group; The results of pathological examination before and after treatment in the two groups showed that the treatment group was obviously superior to the control group, with a significant difference (P 0.05). The results of HP examination in the treatment group and the control group before and after treatment showed that the treatment group was obviously superior to the control group, with a significant difference (P 0.05). Safety indexes were observed before and after treatment of vital signs, blood routine, urine routine, routine routine, liver function of alt ASTU, renal function BUNA Cr UAA) and electrocardiogram were normal. In the course of clinical observation, no adverse reactions were found in the treatment and control groups. Conclusion: the results of the study show that the clinical symptoms of chronic gastritis of Taiyin people can be effectively improved by Taiyin Tiaowei decoction. It can repair gastric mucosa to a certain extent.
【学位授予单位】：延边大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259
，

本文编号：1453128