防风消瘾汤治疗荨麻疹的临床观察与Hp的相关性探讨

发布时间：2018-01-22 03:26

本文关键词： 防风消瘾汤荨麻疹胃肠湿热幽门螺杆菌临床观察　出处：《黑龙江中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:观察防风消瘾汤治疗胃肠湿热型荨麻疹的临床疗效;并探讨荨麻疹的发病与幽门螺杆菌感染之间的关系。方法:选取符合纳入标准荨麻疹患者78例,对照组脱落2例(2例患者均因故中止研究而剔除),最终76例完成临床观察,采用随机对照研究方法,按就诊先后顺序随机分为治疗组和对照组,治疗组39例,对照组37例。治疗组运用防风消瘾汤治疗,对照组口服盐酸依匹斯汀胶囊和西咪替丁片。观察6周,每隔2周复诊一次,分别在2、4、6周各观察一次,记录症状积分情况,6周后统计积分并判定疗效,检测Hp值。观察结束后,隔6周做一次随访,记录复发情况,判断远期疗效。结果:1、治疗6周后两组患者总有效率对比:治疗组总有效率为85.17%,对照组总有效率为54.04%。两组总有效率比较,经秩和检验,P0.05,有显著性差异,结果有统计学意义。提示治疗组疗效优于对照组,防风消瘾汤能明显改善荨麻疹患者的风团症状和瘙痒程度。2、通过与我院健康体检者作对比,慢性荨麻疹患者中幽门螺杆菌感染率明显高于健康对照组。治疗结束后6周随访观察,统计复发率,治疗组荨麻疹复发7例,复发率20.59%,对照组复发9例,复发率45%。治疗组复发率明显低于对照组,防风消瘾汤治疗荨麻疹有较好的远期疗效。结论:1、防风消瘾汤治疗胃肠湿热型荨麻疹疗效显著;副作用小、复发率低,是治疗胃肠湿热型荨麻疹的有效方剂。2、治疗组防风消瘾汤治疗伴有幽门螺杆菌感染的慢性荨麻疹疗效优于对照组口服盐酸依匹斯汀胶囊和西咪替丁片。
[Abstract]:Objective: To observe the clinical curative effect of eliminating wind addiction Decoction in the treatment of gastrointestinal damp heat urticaria; and to explore the relationship between the pathogenesis of urticaria and Helicobacter pylori infection. Methods: 78 cases met the inclusion criteria of patients with urticaria, 2 cases of the control group. (2 cases were excluded, security for Research) finally 76 patients completed clinical observation, a randomized controlled trial, patients were randomly divided into treatment group and control group, 39 cases in the treatment group, 37 cases in the control group. The treatment group used wind fire addiction decoction, control group was treated with Epinastine Hydrochloride Capsules and Cimetidine Tablets. After 6 weeks, every 2 weeks once, respectively in 2,4,6 week observation time, record the symptom integral situation, after 6 weeks of statistical integral and judge the effect, the detection of Hp value. After the observation, every 6 weeks for a follow-up record, recurrence, determine the long-term curative effect. Results: 1, after 6 weeks of treatment, two groups of patients Efficiency comparison: treatment group total effective rate was 85.17%, the total efficiency of the control group 54.04%. total efficiency of two groups, the rank and inspection, P0.05, there are significant differences, the results have statistical significance. Conclusion the curative effect of the treatment group than the control group, the wind fire addiction decoction can obviously improve the symptoms of urticaria urticaria.2 and the degree of itching, through the comparison with our hospital health examination. The rate was significantly higher than the control group of Helicobacter pylori infection in patients with chronic urticaria. 6 weeks after treatment, recurrence rate of treatment group, 7 cases of recurrent urticaria, the recurrence rate was 20.59%, control group 9 cases of recurrence, the recurrence rate of 45%. group the recurrence rate was significantly lower than the control group, the wind fire has better long-term effects of addiction Decoction in the treatment of urticaria. Conclusion: 1. The effect of eliminating wind addiction Decoction in the treatment of gastrointestinal damp heat urticaria significantly; small side effect, low recurrence rate, is the treatment of gastrointestinal damp heat urticaria The effective prescription of.2, the treatment group is better than the wind dissipation of chronic urticaria with addiction Decoction in the treatment of Helicobacter pylori infection in control group were treated with Epinastine Hydrochloride Capsules and Cimetidine Tablets.

【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R275.9

【参考文献】