中药塌渍治疗肝癌（气滞血瘀型）疼痛的临床研究

发布时间：2018-01-23 15:14

本文关键词： 中药塌渍肝癌(气滞血瘀型) 疼痛　出处：《长春中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:观察中药塌渍治疗肝癌(气滞血瘀型)疼痛的临床疗效,证实中药塌渍治疗肝癌疼痛的有效性和安全性。方法:选取72例符合纳入标准的肝癌(气滞血瘀型)疼痛的患者作为研究对象,利用DAS软件产生的随机数字,将其分为治疗组及对照组(各36例)。治疗组给予中药塌渍治疗(将白芍、降香、槟榔、川楝子、莪术、三棱、川乌、乳香、没药研成细末,用水调成糊状敷于患处,每次40分钟,一天两次),对照组给予氨酚曲马多口服治疗。观察两组视觉模拟评分法(VAS)疼痛评分、KPS评分及生活质量评分。结果:在VAS评分方面,治疗组及对照组的VAS评分均降低,组间比较无显著性差异(P0.05);治疗组1例患者完全缓解,30例患者有效,4例患者无效,总有效率为88.5%;对照组2例患者完全缓解,28例患者有效,4例患者无效,总有效率为88.0%,两组总有效率相近,无显著性差异(P0.05)。在KPS评分方面,治疗组与对照组相近,无显著性差异(P0.05)。在生活质量评分方面,治疗组生活质量总评分优于对照组,有显著性差异(P0.05);分项中疲乏、恶心、呕吐、便秘对比,治疗组优于对照组,有显著性差异(P0.05);分项中食欲、精神、睡眠、家庭理解与配合、同事的理解与配合(包括领导)、自身对癌症的认识、日常生活、面部表情对比,两组无显著性差异(P0.05)。结论:中药塌渍能有效缓解肝癌(气滞血瘀型)疼痛,提高患者的生活质量,并且无明显毒副作用、简单易行、安全可靠,为临床治疗肝癌疼痛提供安全有效的方法。
[Abstract]:Objective: to observe the clinical efficacy of traditional Chinese medicine (TCM) in the treatment of liver cancer (Qi stagnation and blood stasis type) pain. Methods: 72 patients with liver cancer pain (Qi stagnation and blood stasis type) were selected as the study object. According to the random numbers produced by DAS software, it was divided into treatment group (36 cases) and control group (36 cases each). The treatment group was treated with traditional Chinese medicine (Paeoniae Alba, Chiangxiang, Betelnut, Toosendan, Curcuma, Sanleng, Chuanwu). Frankincense, myrrh and fine powder were mixed with water to paste the affected area for 40 minutes each time, twice a day. The control group was treated by oral administration of aminophenol tramadol. The visual analogue score (VASs) was observed in both groups. Results: in the aspect of VAS score, the VAS score of the treatment group and the control group decreased, but there was no significant difference between the two groups (P 0.05). In the treatment group, one patient had complete remission and 30 patients were effective and 4 patients had no effect. The total effective rate was 88.5. In the control group, 2 cases of complete remission were effective in 28 cases and 4 cases were ineffective, the total effective rate was 88.0. The total effective rate of the two groups was similar, and there was no significant difference between the two groups (P 0.05). In the aspect of KPS score, there was no significant difference between the two groups. There was no significant difference between the treatment group and the control group (P 0.05). In terms of quality of life score, the total quality of life score in the treatment group was better than that in the control group, and there was significant difference between the treatment group and the control group (P 0.05). Fatigue, nausea, vomiting and constipation in the treatment group were better than those in the control group (P 0.05). Itemized appetite, spirit, sleep, family understanding and cooperation, co-workers' understanding and cooperation (including leadership, their own understanding of cancer, daily life, facial expression contrast. There was no significant difference between the two groups (P 0.05). Conclusion: traditional Chinese medicine can effectively relieve the pain of liver cancer (qi stagnation and blood stasis type), improve the quality of life of patients, and no obvious side effects, simple, safe and reliable. To provide a safe and effective method for the treatment of liver cancer pain.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R273

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