温补心肾法治疗失眠的临床研究

发布时间：2018-01-26 02:07

  本文关键词： 失眠 心肾阳虚证 临床研究　出处：《山东中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：应用温补心肾法,以导师经验方加味桂甘龙牡汤治疗失眠患者,观察其临床疗效,以验证从心肾阳虚治疗失眠的临床可行性,探讨心肾阳虚导致失眠的机理,发掘中医药治疗失眠的方法。方法：选取符合标准的病例60例,随机分为治疗组和对照组各30例,治疗组予加味桂甘龙牡汤,水煎服日一剂。对照组予阿昔唑仑口服,每晚1片。两组均治疗4周为1疗程,治疗4周后判定临床疗效及匹茨睡眠质量指数评分、TDL生命质量评分的变化。结果：临床总有效率治疗组86.67%,对照组60.00%,经统计学处理表明,治疗组优于对照组(P=0.000.01)；同时治疗组中医证候积分、匹茨堡睡眠质量指数评分、TDL生命质量评分均明显改善。结论：具有温补心肾作用的加味桂甘龙牡汤能明显改善患者的症状,并能显著改善其生理心理状态,对其个人、家庭、社会大有裨益,从心肾阳虚治疗失眠确有良好的临床疗效。
[Abstract]:Objective: to observe the clinical effect of Gui Gan long Mu decoction (GDG) in treating insomnia by warming the heart and reinforcing the heart and kidney, and to verify the clinical feasibility of treating insomnia with deficiency of heart and kidney yang. To explore the mechanism of insomnia caused by deficiency of heart and kidney yang and explore the treatment methods of insomnia with traditional Chinese medicine. Methods: 60 cases of insomnia were selected and randomly divided into treatment group and control group of 30 cases each. The treatment group was treated with modified Gui Gan long Mu Tang, one dose of water decoction, and the control group was given aloxazolam orally, one tablet per night. Both groups were treated for 4 weeks as a course of treatment. After 4 weeks of treatment, the clinical efficacy and the score of pitz sleep quality index were evaluated. Results: the total clinical effective rate was 86.67 in the treatment group and 60.00g in the control group, which was demonstrated by statistical analysis. The treatment group was superior to the control group (P < 0.01). At the same time, the TCM syndromes score, Pittsburgh sleep quality index score and TDL quality of life score were improved significantly in the treatment group. Conclusion: the modified Gui Gan long Mu decoction with the effect of warming heart and kidney can obviously improve the symptoms of the patients. It can significantly improve its physiological and psychological state, and is of great benefit to its individual, family and society. There is a good clinical effect in treating insomnia with deficiency of heart and kidney yang.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R256.23

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