2型糖尿病中医证型与眼底病变相关性研究

发布时间：2018-01-27 11:25

  本文关键词： 糖尿病 糖尿病视网膜病变 中医证型　出处：《大连医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:通过究是经过针对150例2型糖尿病临床病例患者搜集的信息以及相关数据,想要通过本次研究进一步的分析出2型糖尿病视网膜病变与2型糖尿病中医辩证型关联,在此基础之上能够深层次的分析出2型糖尿病眼底视网膜其不断改变的特征,从而再将其与2型糖尿病两者完成一定的对比探究,通过视网膜眼底病变的进行性改变更好的防治2型糖尿病提供一定的帮助,反之,我们需要糖尿病眼底视网膜辩证分型变化来更好的帮助2型糖尿病中医辩证分型和治疗。方法:采用回顾性分析的调查的办法,完成整体性的研究。采集相关指标的全部研究对象来自于2015年1月至2017年1月在大连医科大学附属第二院中医病房和内分泌科2型糖尿病患者,按照患者中医四诊的资料和数据把患者区别成几种不同的类型,主要是阴虚热盛型,气阴两虚型,阴阳两虚型,血瘀脉络型。并摘录其详细的病史记录情况,包括患者姓名、年龄,病史,眼底病变,查体等等各种辅助检查信息和内容的采集。把输入与记载全面的具体的详细的探析指标在中医不同的证型组中来深层次的完成一定的对比和探究,探讨其相关性。结果:(1)性别、体重指数、年龄无显著性差异(P0.05),2型糖尿病的发病过程中以气阴两虚证为主,吸烟史中医证型之间有显著差异,气阴两虚证与阴阳两虚证存在差异明显(P0.05),其它证型无明显差异(p0.05)。(2)中医各证型组之间病程有显著性差异(P0.05),病程会随着证型逐渐加重(3)中医各证型组与甘油三醋、胆固醇、低密度脂蛋白基本上无显著性差异(P0.05),高密度脂蛋白较其他组有明显差异,阴阳两虚证和阴虚热盛两组之间存在差异(P0.O5),气阴两虚证与阴虚热盛证两组存在差异(P=0.05),其它之间没有差异(P0.05)(4)各证型组之间从视网膜眼底变化来看,血管瘤以气阴两虚证型最为明显(P0.05),阴虚热盛组,阴阳两虚组与血癖脉络组无明显差异(P0.05)。阴阳两虚组中新生血管及黄斑水肿表现明显高于其他各组(P0.05,)气阴两虚组、阴虚热盛组与血癖脉络组无明显差异(P0.05);玻璃体积血以血瘀阻络型为主(P0.05),其他无显著性差异(P0.05);结论:本研究的结果显示,龄、性别、体重指数无显著性差异,2型糖尿病的发病过程中以气阴两虚证为主,吸烟会加重糖尿病病情;站在病程的角度来观察,中医辩证分型阴虚热盛证、气阴两虚证、血癖脉络证阴阳两虚证的病程是呈逐渐增长的趋势的。并且随着疾病的进程,脂代谢紊乱变得更加严重;糖尿病视网膜眼底病变中血管瘤以气阴两虚证型最为明显。阴阳两虚组中新生血管及黄斑水肿表现明显高于其他各组;玻璃体积血以血瘀阻络型为主,其它各组无明显差别;符合中医消渴发病进程,说明糖尿病视网膜眼底病变的发病率与2型糖尿病中医辩证分型关系十分密切,有助于中医辩证客观规律化;若是迎合中医消渴发病进程,那就意味着糖尿病视网膜眼底病变的发病率和2型糖尿病中医辩证分型有着非常紧密的联系,诸多方面有着深层次的影响,可以让我们能够更好的理解医辩证客观规律赋予一定的帮助;在治疗2型糖尿病的过程中,我们需要主动的完成监测工作,想要更好的掌握疾病的进程,随之我们需要尽快和及时的完成一定的预防工作,由此一来,能够比较全面和有效合理的延迟疾病的发展情形,并能减少疾病的恶化。
[Abstract]:Objective: To study the information collected after 150 cases of patients with type 2 diabetes clinical cases and relevant data, through this research to further analysis of type 2 diabetic retinopathy in patients with type 2 diabetes mellitus TCM Association, based on deeply analysis of the changing of fundus type 2 diabetic retinopathy thus, the type 2 diabetes mellitus and explore both complete certain changes in contrast, better prevention and treatment of type 2 diabetes to provide some help, but by retinopathy, we need diabetes retinal dialectical type changes to help the Chinese type 2 diabetes diagnosis and treatment. Methods: the retrospective investigation and analysis to complete the overall study. Collecting related index of all subjects from January 2015 to January 2017 in Dalian hospital Department of the Second Affiliated Hospital of Chinese medicine university affiliated ward and Department of Endocrinology patients with type 2 diabetes, the difference between patients into several different types of patients according to TCM data, mainly exuberant heat due to yin deficiency, deficiency of Qi and Yin, yin and yang two deficiency, blood stasis syndrome and its extract. Detailed records, including patient name, age history, fundus examination, auxiliary examination and so on all kinds of information and content acquisition. The input and record the specific comprehensive detailed analysis of the indicators to deep in syndrome type TCM group in different ratio and to complete certain inquiry, to explore their correlation. Results: (1) gender, body mass index. There was no significant difference in age (P0.05) and the pathogenesis of type 2 diabetes in two Qi and yin deficiency syndrome, there is significant difference between the TCM syndrome type of smoking history, deficiency of Qi and yin deficiency syndrome of yin and yang two two and there were significant differences (P0.05), other certificate 鍨嬫棤鏄庢樉宸�寮�(p0.05).(2)涓�鍖诲悇璇佸瀷缁勪箣闂寸梾绋嬫湁鏄捐憲妫�

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