基于数据挖掘的乙脑急性期中医用药规律研究

发布时间：2018-01-30 18:50

本文关键词： 乙型脑炎急性期中医治疗数据挖掘关联规则聚类算法　出处：《辽宁中医杂志》2017年05期 　论文类型：期刊论文

【摘要】：目的:探讨乙脑急性期的中医用药特点及规律。方法:计算机检索乙脑急性期中医证治文献,提取医案的中医四诊信息,经过数据标准化处理并建立数据库,运用中医传承辅助系统挖掘其用药规律。结果:共纳入文献205篇,医案257例。核心药物为石膏、知母、金银花、连翘、生地黄、钩藤,核心组合16个,并推演出候选新处方8个。结论:乙脑急性期的中医用药应依据卫气营血辨证选择主药,并遵循"清热、开窍、熄风止痉"三大原则,重视泻下药在清热法中的运用,为临床治疗提供依据和指导。
[Abstract]:Objective: to explore the characteristics and regularity of traditional Chinese medicine in acute stage of encephalitis B. Methods: to search the literature of syndrome and treatment of Japanese encephalitis in Chinese medicine, to extract the information of four diagnoses of traditional Chinese medicine (TCM), to standardize the data processing and to set up a database. Results: 205 documents and 257 medical cases were included. The core drugs were gypsum, Anemarrhena, honeysuckle, Forsythia suspensa, Radix Rehmanniae and Uncaria. The core combination was 16, and 8 new prescriptions were deduced. Conclusion: the traditional Chinese medicine in acute stage of encephalitis B should choose the main medicine according to the differentiation of Wei Qi and Ying blood, and follow the three principles of "clearing heat, opening the orifices, quashing wind and stopping spasmolysis". Attach importance to the application of catharsis medicine in clearing away heat, and provide basis and guidance for clinical treatment.
【作者单位】：中国中医科学院眼科医院;中国中医科学院中医临床基础医学研究所;中国中医科学院中医药发展研究中心;中国中医科学院;
【基金】：“十二五”国家科技重大专项资助项目(2012ZX10004301-001)
【分类号】：R259
【正文快照】： 流行性乙型脑炎(简称乙脑),是由乙型脑炎病毒引起以脑实质炎症为主要病变的中枢神经系统急性传染病。本病多急性起病,具有传染性、流行性、季节性和地域性的特点。病程上一般分为初期、极期、恢复期及后遗症期,其中初期、极期属急性期[1],是病情转归的关键,可见高热、意识障碍

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