针药结合治疗反流性食管炎疗效观察

发布时间：2018-01-31 21:56

本文关键词： 反流性食管炎化浊解毒降逆方针刺疗法反流性疾病问卷　出处：《中国针灸》2017年07期 　论文类型：期刊论文

【摘要】：目的:比较化浊解毒降逆方结合针刺治疗反流性食管炎与西药奥美拉唑以及单纯服用中药的临床疗效差异。方法:将90例反流性食管炎患者随机分为3组,脱落病例4例,最后针药组29例、西药组29例、中药组28例纳入统计。针药组口服化浊解毒降逆中药方并针刺内关、足三里、中脘、肝俞、胆俞、太冲,中药每日1剂,针刺每日1次;西药组口服奥美拉唑胶囊20 mg,每日2次;中药组单纯口服化浊解毒降逆方。3组均治疗8周,随访6个月。观察3组患者治疗前后反流性疾病问卷(RDQ)评分、胃镜下食管黏膜的变化,并评定临床证候疗效以及复发率。结果:治疗4周、8周后3组RDQ积分均较治疗前下降(均P0.05),治疗4周后针药组RDQ积分低于西药组(P0.05),治疗8周后针药组RDQ积分低于西药组与中药组(均P0.05);随访6个月,针药组复发率低于其他两组(均P0.05);治疗8周后针药组证候总有效率及胃镜总有效率均优于西药组与中药组(均P0.05)。结论:化浊解毒降逆方结合针刺治疗反流性食管炎疗效确切,可改善症状,保护胃黏膜,减少复发率,疗效优于单纯中药和西药奥美拉唑。
[Abstract]:Objective: to compare the clinical efficacy of Huazhuojiedu Jiangni prescription (Huazhujiedu Jiangni) combined with acupuncture in the treatment of reflux esophagitis. Methods: 90 patients with reflux esophagitis were randomly divided into 3 groups. There were 4 cases of abscission, 29 cases of acupuncture and medicine group, 29 cases of western medicine group and 28 cases of traditional Chinese medicine group. The acupuncture and medicine group took orally the prescription of removing turbid and detoxifying and lowering the adverse effect of traditional Chinese medicine and acupuncture on Neiguan, Zusanli, Zhongwan, Ganshu, Danshu, Taichong. Traditional Chinese medicine 1 dose daily, acupuncture once daily; The western medicine group took omeprazole capsule 20 mg twice a day; All the patients in the traditional Chinese medicine group were treated for 8 weeks and followed up for 6 months. The RDQs and the changes of esophageal mucosa under gastroscope were observed before and after treatment. Results: after 4 weeks and 8 weeks of treatment, the RDQ scores of the three groups were lower than those before treatment (all P 0.05). After 4 weeks of treatment, the RDQ score in the acupuncture and medicine group was lower than that in the western medicine group, and the RDQ score in the acupuncture and medicine group was lower than that in the western medicine group and the traditional Chinese medicine group after 8 weeks (all P 0.05). The recurrence rate in the acupuncture and medicine group was lower than that in the other two groups (P 0.05). After 8 weeks of treatment, the total effective rate of syndrome and gastroscope in acupuncture and medicine group were better than those in western medicine group and traditional Chinese medicine group (P 0.05). Conclusion: Huazhuo jiedu Jiangni prescription combined with acupuncture is effective in the treatment of reflux esophagitis. It can improve symptoms, protect gastric mucosa and reduce recurrence rate. The curative effect is better than omeprazole.
【作者单位】：河北省中医院脾胃病科;河北中医学院;河北医科大学研究生院;河北省中医药科学院;
【基金】：国家中医药管理局全国名老中医药专家传承工作室建设项目:国中医药人教发[2014]20号河北省浊毒证重点实验室
【分类号】：R246.1
【正文快照】： 反流性食管炎(reflux esophagitis,RE)是指胃内容具备主症2项加次症2项。物反流入食管、口腔(包括喉部)或肺所致的症状和并1.3纳入标准发症[1]。反流性食管炎为临床常见病、多发病,其发病年龄18~70岁者;临床诊断为RE及RDQ积分率呈上升趋势。西医学认为其发病机制主要是食管高

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