益气养阴活血通络法治疗早期糖尿病肾病26例临床观察

发布时间：2018-02-12 10:28

本文关键词： 糖尿病肾病尿白蛋白/尿肌酐比值中西医结合疗法益气养阴活血通络　出处：《中国中医基础医学杂志》2017年09期 　论文类型：期刊论文

【摘要】：目的:观察中西医结合疗法治疗气阴两虚络阻型糖尿病肾病早期的临床疗效。方法:选择气阴两虚络阻型早期糖尿病肾病患者47例,随机将其分为治疗组26例及对照组21例。对照组接受降血糖、降血压、抗血小板聚集等西医基础治疗措施,治疗组加服益气养阴活血通络中药汤剂,观察2组糖尿病肾病疗效及中医证候疗效;治疗前后分别观察2组患者血脂、尿白蛋白(UAlb)、尿肌酐(UCr)、尿白蛋白与尿肌酐比值(ACR)。结果:治疗组中医证候疗效和糖尿病肾病疗效均优于对照组,差异有统计学意义。治疗组治疗后UAlb、UCr、ACR、TC、TG水平均较治疗前显著降低,HDL-C水平较治疗前显著升高,且治疗后治疗组UAlb、ACR、TC、TG水平显著低于对照组,HDL-C水平显著高于对照组。结论:在西医常规治疗基础上配合益气养阴活血通络中药可明显提高糖尿病肾病早期疗效。
[Abstract]:Objective: to observe the clinical effect of combined therapy of traditional Chinese and western medicine on the early stage of diabetic nephropathy with deficiency of qi and yin and deficiency of collaterals and collaterals. Methods: 47 cases of early diabetic nephropathy of the type of deficiency of qi and yin and deficiency of collaterals were selected. It was randomly divided into treatment group (n = 26) and control group (n = 21). The control group received basic western medicine treatment such as lowering blood glucose, lowering blood pressure and anti-platelet aggregation, and the treatment group was treated with traditional Chinese medicine decoction of supplementing Qi, nourishing Yin and activating Blood Circulation. Observe the curative effect of diabetic nephropathy and TCM syndromes, observe the blood lipid of the two groups before and after treatment, Results: the therapeutic effect of TCM syndrome and diabetic nephropathy in the treatment group was better than that in the control group, and the ratio of urinary albumin to urinary creatinine was higher than that of the control group. In the treatment group, the levels of UAlbbumin and UCRTCU TG were significantly lower than those before treatment, and the level of HDL-C was significantly higher than that before treatment, and there was no significant difference between the treatment group and the control group. After treatment, the level of TG in the treatment group was significantly lower than that in the control group (P < 0.05). Conclusion: on the basis of routine western medicine treatment, combined with traditional Chinese medicine for supplementing qi, nourishing yin and activating blood circulation, can obviously improve the early curative effect of diabetic nephropathy.
【作者单位】：安徽中医药大学第三附属医院内分泌科;安徽省界首市人民医院内分泌科;
【分类号】：R259

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