蜂针治疗类风湿关节炎Meta分析

发布时间：2018-02-20 23:57

本文关键词： 蜂针类风湿关节炎 Meta分析系统评价　出处：《中华中医药学刊》2017年05期 　论文类型：期刊论文

【摘要】：目的:系统评价单用蜂针或蜂针联合其他方法治疗类风湿性关节炎的效果。方法:检索中国生物医学文献数据库(CBM)、万方数据资源系统(Wan Fang Data)、中国知网(CNKI)、中文科技期刊数据库(VIP)截至2016年3月29日的文献,用Cohrane协作网系统综述手册5.0标准评价文献质量,用Rev Man 5.2软件进行Meta分析。结果:纳入文献11篇,共738例;单用蜂针的总有效率高于布洛芬+中药制剂(P0.05);单用蜂针与甲氨蝶呤、单用蜂针与甲氨蝶呤+塞来昔布的总有效率比较无显著差异(P0.05);蜂针+甲氨蝶呤与甲氨蝶呤、蜂针+甲氨蝶呤+柳氮磺吡啶+美洛昔康与甲氨蝶呤+柳氮磺吡啶+美洛昔康、蜂针+中药熏洗+芬必得+来氟米特+甲氨蝶呤与芬必得+来氟米特+甲氨蝶呤、蜂针+中药外敷+青霉素+双氯芬酸钠与青霉素+双氯芬酸钠的总有效率均是前者高于后者(P0.05或P0.01);蜂针+养血通痹汤与非甾体类消炎镇痛药+激素、蜂针+雷公藤与雷公藤的总有效率比较无显著差异(P0.05)。结论:单用蜂针或联合蜂针能提高类风湿关节炎的疗效,但需更多高质量、大样本的随机对照试验证实。
[Abstract]:Objective: to systematically evaluate the efficacy of bee needle or bee needle combined with other methods in the treatment of rheumatoid arthritis. Methods: to search the Chinese Biomedical Literature Database (CBM), Wanfang data Resource system (Wan Fang data), Chinese Science and Technology (CNKI). Journal Database (VIP) as of March 29th 2016, The quality of the literature was evaluated with the Cohrane Cooperative Network Review Manual 5.0, and the Meta analysis was carried out with Rev Man 5.2 software. Results: the total effective rate of single bee needle was higher than that of ibuprofen traditional Chinese medicine preparation (P0.05), and that of bee needle and methotrexate was higher than that of ibuprofen traditional Chinese medicine preparation (P0.05), the total effective rate of bee needle was higher than that of ibuprofen preparation. There was no significant difference in the total effective rate between single bee needle and methotrexate celecoxib, there was no significant difference between bee needle methotrexate and methotrexate, bee needle methotrexate and methotrexate azepyridine meroxicam and methotrexate azepyridine meroxicam, The Chinese medicine of bee needle fumigation and washing fentanyl get leflunomide methotrexate and fenbim get leflunomide methotrexate, The total effective rate of penicillin diclofenac sodium and penicillin diclofenac sodium was higher than that of penicillin diclofenac sodium compared with that of penicillin diclofenac sodium. There was no significant difference in the total effective rate between Tripterygium wilfordii and Tripterygium wilfordii. Conclusion: single bee needle or combined bee needle can improve the curative effect of rheumatoid arthritis, but it needs more high quality.
【作者单位】：广州中医药大学;广州医科大学附属第三医院;
【基金】：国家自然科学基金青年科学基金项目(81403488)
【分类号】：R246.1

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