清利化瘀止痒方治疗慢性肾衰竭皮肤瘙痒的临床观察

发布时间：2018-02-24 06:46

本文关键词： 慢性肾衰竭皮肤瘙痒清利化瘀止痒方湿热血瘀证　出处：《黑龙江中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:应用清利化瘀止痒方治疗慢性肾衰竭患者皮肤瘙痒,观察中医药治疗慢性肾衰竭皮肤瘙痒的临床疗效。方法:选取2016年3月至2017年1月黑龙江中医药大学附属第一医院肾内科门诊,中医辨证类型属于湿热血瘀证,并符合慢性肾衰竭皮肤瘙痒纳入标准的患者40例。在西医常规治疗的基础上,给予患者口服清利化瘀止痒方治疗,每日1剂,水煎2次共约300ml,混匀,早晚2次温服,4周为一个疗程。采取自身前后对照法进行观察,观察患者治疗前后的临床疗效和中医症状积分,比较治疗前后皮肤瘙痒的积分变化及相关实验室指标的改变,观察清利化瘀止痒方的临床疗效。结果:清利化瘀止痒方治疗CRF患者皮肤瘙痒总有效率是77.78%;中医证候总有效率为80.56%;经清利化瘀止痒方治疗后,患者皮肤瘙痒症状明显缓解,瘙痒评分显著下降(P0.01);肾功能明显改善,Scr、BUN治疗后均显著下降(P0.01),Ccr升高(P0.01);中医症状积分显著下降(P0.01)。结论:1、清利化瘀止痒方治疗慢性肾衰竭(湿热血瘀证)皮肤瘙痒能有效改善患者皮肤瘙痒的症状。2、清利化瘀止痒方能有效降低慢性肾衰竭患者的血肌酐、尿素氮,提高内生肌酐清除率,改善肾脏功能。3、清利化瘀止痒方治疗慢性肾衰竭能有效缓解患者各项不适症状,降低中医症状积分,改善患者全身状态。
[Abstract]:Objective: to apply Qingli Huayu Zhiyang recipe to treat skin pruritus in patients with chronic renal failure. To observe the clinical effect of traditional Chinese medicine on chronic renal failure (CRF) skin itching. Methods: from March 2016 to January 2017, the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine was selected. On the basis of western medicine routine treatment, the patients were given oral Qingli Huayu Zhiyang prescription, 1 dose per day, water decoction for 2 times, about 300 ml, mixed well, and 40 cases of chronic renal failure skin pruritus were included in the standard. To observe the clinical curative effect and TCM symptom score of the patients before and after treatment, and to compare the integral changes of skin pruritus and related laboratory indexes before and after treatment. Results: the total effective rate of Qingli Huayu Zhiyang recipe for treating skin pruritus in patients with CRF was 77.78; the total effective rate of TCM syndrome was 80.56; after the treatment of Qingli Huayu Zhiyang recipe, the symptoms of skin pruritus were obviously alleviated. The score of pruritus decreased significantly (P 0.01); the renal function improved significantly after treatment with Scrbun; the increase of CCR was significantly decreased after treatment; the score of symptoms of traditional Chinese medicine decreased significantly (P 0.01). Conclusion the pruritus of chronic renal failure (damp-heat and blood stasis) can be treated with "Wei 1", "Qingli Huayu Zhiyang prescription". [WT5 "HZ] [WT5BZ] it is possible to treat chronic renal failure (dampness, heat and blood stasis) with pruritus. It can effectively reduce serum creatinine in patients with chronic renal failure. Urea nitrogen, improving the clearance rate of endogenous creatinine, improving renal function... Qingli Huayu Zhiyang prescription can effectively relieve the symptoms of patients with chronic renal failure, reduce the integral of TCM symptoms, improve the patients' general state.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R275.9

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