大柴胡汤加味治疗慢性胆囊炎（肝胆实热证）的临床观察

发布时间：2018-02-27 06:15

本文关键词： 大柴胡汤加味慢性胆囊炎肝胆实热证临床观察　出处：《长春中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:本课题为中医学经典方剂大柴胡汤加味治疗慢性胆囊炎(肝胆实热证)的临床研究。通过本研究欲评价大柴胡汤加味治疗慢性胆囊炎(肝胆实热证)的药理活性及治疗效果,借此也进一步探究中医方剂治病的机制和疗效,体现中国古代医学的科学性和优势所在,对我国中医药理研究和发展具有促进和借鉴作用。方法:本研究患者均来自长春中医药大学肝胆脾胃病科门诊,并符合纳入标准的60例经慢性胆囊炎(肝胆实热证)作为研究对象,采用了随机对照分组法,对所有病人做了合理分组处理,分别为30例治疗组和30例对照组。治疗组给予大柴胡汤加味中药汤剂,对照组给予广州白云山中一药业有限公司的胆康片(国药准字Z44022447)。给药方面,治疗组和对照组均经过4周连续给药,这期间对患者的所有症状表现都做了严格科学的记录,包括了患者常规生理参数、疾病相关症状变化及腹部彩超的变化,最后采用统计学方法对结果进行了分析,给出结论。结果:本实验经过合理的设计,选取60位研究对象并均分成治疗组和对照组两组进行实验。最后得出:治疗组30例所有患者都有效,总有效率为100%,且其中14位患者表现为明显的症状改善,对照组30例患者有效25例,无效5例,总有效率为83.3%。观察主要临床症状的改善情况,治疗组治疗前总积分平均值为12.68±1.47,治疗后为4.08.±0.99;而对照组在治疗前后这两个参数分别为12.96±1.65和7.98±1.45。进而,综合分析治疗有效率、症状积分及其他测量参数,采用统计学差异显著性分析方法进行评价,得出治疗组的个项指标与对照组相比都有显著的差异(P0.05),统计学意义显著。由此得出,采用大柴胡汤加味治疗本病疗效优于胆康片。结论:大柴胡汤加味治疗慢性胆囊炎(肝胆实热证),可明显缓解症状。
[Abstract]:Objective: this research for TCM classical prescription of Dachaihu Decoction Treatment of chronic cholecystitis (liver heat syndrome) clinical research. Through this study to evaluate the Dachaihu Decoction Treatment of chronic cholecystitis (liver heat syndrome) the pharmacological activity and therapeutic effect, and also to further explore the mechanism and effect of treatment of traditional Chinese medicine prescriptions, reflect China ancient medical science and has the advantage, promotion and reference for the research and development of Chinese medicine pharmacology. Methods: This study patients from the Changchun University of Traditional Chinese Medicine Department of liver and spleen clinic, and in accordance with the inclusion criteria of 60 cases with chronic cholecystitis (liver heat syndrome) as the research object, using a randomized grouping method. All patients had made reasonable packet processing, 30 cases were in treatment group and 30 cases in control group. The treatment group was given Dachaihu Decoction of Chinese medicine decoction, the control group was given the Guangzhou Baiyun Mountain A pharmaceutical company of Qindankechuankang tablets (Zhunzi Z44022447). For the medicine, the treatment group and the control group after 4 weeks of continuous administration, this period has done a rigorous scientific record of all symptoms of patients, including patients with normal physiological parameters, change of disease related symptoms and changes of abdomen color Doppler ultrasound, the results were analyzed by statistical method, the conclusion is given. Results: through this experiment, reasonable design, selection of the 60 subjects were divided into treatment group and control group two groups. The treatment group of 30 cases of all patients were effective, the total effective rate was 100%, and the 14 patients showed obvious improvement of symptoms, 30 patients in the control group 25 cases effective, 5 cases ineffective, the total efficiency of 83.3%. to observe the improvement of main clinical symptoms, the treatment group total score before treatment with an average of 12.68 + 1.47, 4.08. + 0.99 after treatment ; while the control group before and after treatment of the two parameters were 12.96 + 1.65 and 7.98 + 1.45. and comprehensive analysis of the efficiency of treatment, symptoms and other parameters were analyzed by statistical significant difference analysis method, the indexes obtained in the treatment group compared with the control group had significant difference (P0.05), statistically significant. Thus, the Dachaihu Decoction in the treatment of this disease curative effect is better than that of Qindankechuankang tablets. Conclusion: Dachaihu Decoction Treatment of chronic cholecystitis (liver heat syndrome), can significantly relieve the symptoms.

【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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