金枳术石汤治疗泌尿系结石（湿热气滞型）临床疗效观察

发布时间：2018-02-27 08:41

本文关键词： 金枳术石汤泌尿系结石湿热气滞肾石通颗粒临床观察　出处：《成都中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：通过金枳术石汤治疗泌尿系结石(湿热气滞型)的临床观察研究,对该方产生的疗效和安全性进行初步评价。并对中医治疗泌尿系结石的治疗规律进行探讨。方法：依据本试验的纳入标准及排除标准,对符合条件的42例受试者采用随机、对照临床试验的方法,将其分为治疗组(金枳术石汤)和对照组(肾石通颗粒)。疗程4周。观察两组受试者治疗前后的临床综合疗效、无石率、中医证候积分、尿液分析、泌尿系彩超等方面的情况,并根据试验所得数据,做出初步的疗效及安全性评价。结果：本试验治疗组总有效率85.71%,对照组总有效率71.42%,两组总有效率比较具有统计学意义P0.05；治疗后治疗组与对照组的尿白细胞计数、尿红细胞计数比较具有统计学意义,P0.05。中医证侯疗效治疗组有效率90.47%,对照组有效率80.95%,治疗后两组中医证候积分比较具有统计学意义,P0.05。安全性观察中,未见与用药相关的皮疹、消化道反应、皮肤瘀点瘀斑等不良反应。结论：金枳术石汤不仅可以有效促进泌尿系结石(湿热气滞型)患者的结石排出,而且可以有效缓解泌尿系结石患者的腰腹疼痛、尿频尿急、血尿等临床症状。有效的减少尿红细胞、尿白细胞。在与肾石通颗粒的疗效比较中发现,金枳术石汤优于肾石通颗粒,安全性良好。
[Abstract]:Objective: to observe the clinical effect of Jinzhi Zhushi decoction in the treatment of urinary calculi (damp heat qi stagnation type). To evaluate the curative effect and safety of this prescription, and to discuss the treatment rule of traditional Chinese medicine for urinary calculi. Methods: according to the inclusion standard and exclusion standard of this experiment, 42 subjects who met the requirements were randomly used. The methods of clinical trial were compared and divided into two groups: the treatment group (Jinzhi Zhushi decoction) and the control group (Shenshi Tong granule) for 4 weeks. The clinical comprehensive curative effect, stone free rate, TCM syndromes integral, urine analysis were observed before and after treatment in the two groups. The status of urography and other aspects, and according to the data obtained from the test, Results: the total effective rate of the treatment group was 85.71, the total effective rate of the control group was 71.42, and the total effective rate of the two groups was significantly higher than that of the control group (P 0.05). The effective rate of the treatment group was 90.47 and that of the control group was 80.95.The score of TCM syndromes in the two groups was statistically significant after treatment. No rash related to medication was found in the safety observation. Conclusion: Jinzhi Zhushi decoction can not only effectively promote the excretion of stones in patients with urinary calculi (damp-heat qi stagnation type), but also alleviate the pain of waist and abdomen in patients with urinary calculi. Frequent urination, hematuria and other clinical symptoms. Effectively reduce urine red blood cells, urine white blood cells. In comparison with Shenshi Tong granule, Jinzhi Zhushi decoction is superior to Shenshi Tong granule, the safety is good.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.5

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