基于关联规则三叉神经痛近十五年中医用药规律研究

发布时间：2018-02-28 17:17

本文关键词： 三叉神经痛关联规则方药规律　出处：《山东中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:采用关联规则分析三叉神经痛中药治疗规律,拓展中医治疗三叉神经痛的用药思路。方法:收集近十五年(2001年-2015年)期刊发表的中医药治疗三叉神经痛的文献,根据纳入标准筛选文献,并整理其中药物,用SPSS统计软件建立三叉神经痛方数据库进行频数分析,运用SPSS Clementine 12.0软件分析方剂中各药物之间的关联程度、药物组成及配伍规律。结果:共搜集方剂155首,涉及中药161味,经频数分析得出中药总频数1637次。使用不低于10次的药物39味,共1302次,占总频数的79.54%。以川芎使用频数最多,为106次,其次是甘草、全蝎、白芷、白芍;其中又以解表药频次最高,共413次,占总频数的25.23%,其次为平肝息风药、补虚药等。经关联规则算法分析得到药物间有意义的关联规则303条,以川芎所含规则数最多,共184条,占总规则的60.73%。置信度达100%的规则10条,10条均包含川芎。结论:治疗三叉神经痛以解表药及平肝息风药为主,并常与补虚药、活血化瘀药、清热药、化痰止咳平喘药、利水渗湿药等配伍运用。川芎是治疗三叉神经痛的首选药物。运用关联规则研究方药配伍规律有效可行。
[Abstract]:Objective: to analyze the law of traditional Chinese medicine treatment of trigeminal neuralgia by using association rules, and to expand the thinking of traditional Chinese medicine in the treatment of trigeminal neuralgia. Methods: the literature on the treatment of trigeminal neuralgia published in the recent fifteen years (2001 to 2015) was collected. According to the standard literature, the drugs were sorted out, and the frequency of trigeminal neuralgia formula database was established by SPSS software. The correlation degree of each drug in the prescription was analyzed by SPSS Clementine 12.0 software. Results: a total of 155 prescriptions were collected, involving 161 kinds of Chinese medicines. The total frequency of traditional Chinese medicine was 1 637 times by frequency analysis. 39 kinds of drugs were used for not less than 10 times (1302 times), accounting for 79.54% of the total frequency. The use frequency of Chuanxiong Rhizoma Chuanxiong was the most. 106 times, followed by liquorice, scorpion, angelica dahurica, paeoniae aleoniae, among them, the antitabular drug frequency was the highest (413 times), accounting for 25.23 times of the total frequency, followed by calming the liver and relieving wind medicine. Through the analysis of association rules algorithm, 303 meaningful association rules were obtained, of which Chuanxiong had the largest number of rules, altogether 184, The 10 rules with confidence of 100% all contain Chuanxiong. Conclusion: the treatment of trigeminal neuralgia is mainly composed of antiphlegm and calming the liver and relieving wind, and often with tonifying drugs, promoting blood circulation, removing blood stasis, clearing away heat, eliminating phlegm and relieving cough and asthma. Chuanxiong is the first choice in the treatment of trigeminal neuralgia.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.7

【参考文献】