新安医学固本培元派医家痹病用药特色研究

发布时间：2018-02-28 21:18

本文关键词： 新安医学固本培元痹病用药规律中医传承辅助系统　出处：《皖南医学院》2016年硕士论文　论文类型：学位论文

【摘要】：目的:借助分析名中医的软件-中医传承辅助系统(TCMISS),重点分析新安医学固本培元派医家治痹的整体用药规律;来自新安地区的“风湿病五老”之一的李济仁教授,崇尚汪机的固本培元思想,继承和发扬了新安医学治痹思想,对符合入选标准的临床病例亦通过TCMISS进行分析;最后比较两者的异同点。方法:以皖南医学院图书馆、皖南医学院第一附属医院(弋矶山医院)国医大师工作室为平台,收集并整理固本培元派医家的临床医案或临床经验,严格按照纳入标准选录,共有6位医家(汪机、孙一奎、程敬通、吴楚、程国彭、程杏轩),其著作依次为《石山医案》、《孙一奎医学全书》、《程敬通医案》、《吴氏医验录全集》、《医学心悟》和《杏轩医案》,有临床验案130例,处方106首,运用中医传承辅助平台,采用规格分析、改进的互信息法、复杂系统熵聚类等数据挖掘方法,对106首处方的药物进行频次分析、规则分析、聚类分析,而产生常用药物、核心组合、及新处方,进而总结新安医学固本培元派医家治痹的用药规律;收集近5年已发表在中国知网的论文中提及的临床验案和已出版的书籍的临床验案共34例,与上述固本培元派医家治痹用药进行对比。结果:1.六位医家的医案中有关治痹药物共有141味,总用药频次为1035次,其中出现频次最高的药物是甘草、当归、人参、白术、茯苓、陈皮、秦艽、肉桂、黄芪、附子、川芎;前10位核心组合分别为人参-白术、人参-当归、人参-茯苓、白术-茯苓、炙甘草-茯苓、炙甘草-白术、炙甘草-人参、白术-当归、人参-黄芪、陈皮-茯苓;进一步产生新方9首。2.李济仁教授临床工作病例处理亦采用中医传承辅助系统,录入和整理所选的34首方剂,从多方面和多角度分析,得到相应的高频用药、核心组合和新方。结论:较为系统地提取了新安医学固本培元派医家治痹医案;通过分析得出了新安医学固本培元派医家治痹的核心方药、常用药物组合及新方;通过异同点的比较,李济仁教授继承和发扬了新安医学固本培元派的学术思想,将古代文献研究结合李教授的现今临床实践,使本课题更富有现代研究意义。
[Abstract]:Objective: by analyzing the software of famous Chinese medicine, the assistant system of traditional Chinese medicine (TCMISS), this paper focused on the analysis of the overall drug use rule of the doctors who sent doctors to treat arthralgia in Xin'an Medicine, and Professor Li Jiren, one of the "five old people with rheumatism" from Xin'an area. Advocating Wang Ji's thought of cultivating Yuan, inheriting and carrying forward the thought of Xin'an medical treatment of arthralgia, and analyzing the clinical cases that meet the criteria of selection through TCMISS. Finally, the similarities and differences between the two are compared. Methods: the library of Southern Anhui Medical College, The Guoyi Master Studio of the first affiliated Hospital of Southern Anhui Medical College (Yaji Shan Hospital) was a platform for collecting and arranging the clinical cases or clinical experience of the medical practitioners sent by the Puiyuan School of Guimen, strictly according to the inclusion criteria. A total of 6 doctors (Wang Ji, Sun Yikui) were selected and recorded, and a total of 6 doctors (Wang Ji and Sun Yikui) were selected and recorded. Cheng Jingtong, Wu Chu, Cheng Guopeng, Cheng Xingxuan, whose works are "Shishan Medical record", "Sun Yi-kui Medical Book", "Cheng Jingtong Medical case", "Wu's Medical examination record complete works", "Medical Heart comprehension" and "Xing Xuan Medical record", has 130 clinical cases and 106 prescriptions. With the aid of traditional Chinese medicine inheritance platform, data mining methods such as specification analysis, improved mutual information method and entropy clustering of complex systems, 106 prescriptions of drugs were analyzed by frequency, rules, clustering, and common drugs were produced. The core combination, and new prescriptions, to sum up the rule of drug use in treating arthralgia by doctors sent by Peiyuan School of Medicine, and to collect 34 cases of clinical cases and published books, which have been published in papers published in China in the past five years. Results: among the six doctors' cases, there were 141 kinds of arthralgia drugs, and the total frequency was 1035. The most frequent drugs were liquorice, angelica sinensis, ginseng, Atractylodes macrocephala, Poria cocos. Chen Pei, Gentiana macrophylla, Cinnamomum Cinnamomi, Astragalus membranaceus, Radix Aconiti, Rhizoma Chuanxiong; the top 10 core combinations are Ginseng-Atractylodes, Ginseng-Angelica sinensis, Ginseng-Poria cocos, Atractylodes macrocephala-Poria cocos, Radix Glycyrrhizae-Fuling, Radix Glycyrrhizae Atractylo@@. Atractylodes macrocephala-Angelica sinensis, Ginseng-Astragalus, Chen Pei-Poria; further produce 9 new prescriptions. 2. Professor Li Jiren's clinical case handling also uses the Chinese Medicine inheritance Assistance system to input and organize 34 selected prescriptions, and analyzes them from many aspects and angles. The corresponding high frequency medicine, core combination and new prescription were obtained. Conclusion: the medical records of treating arthralgia by doctors of Peiyuan School of Medicine in Xin'an Medicine are extracted systematically, and the core prescriptions of treating arthralgia by doctors of Peiyuan School of Medicine in Xin'an Medicine are obtained through analysis. By comparing the similarities and differences, Professor Li Jiren inherited and carried forward the academic thought of the School of Medicine in Xin'an, and combined the study of ancient literature with Professor Li's current clinical practice. Make this subject more modern research significance.
【学位授予单位】：皖南医学院
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R249;R255.6

【相似文献】