不同异常体液型骨性关节炎患者血清Cys-C水平变化的观察研究

发布时间：2018-03-04 06:00

本文选题：维吾尔医　切入点：骨性关节炎　出处：《新疆医科大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:研究膝骨性关节炎患者中血清胱抑素-C在维吾尔医异常体液分型中的变化情况及其相关性;探讨其在维吾尔医膝骨性关节炎异常体液分型中的早期诊断、疾病监测及维吾尔医症候分型中的作用,同时给维吾尔医治疗膝关节炎补肾原则提供理论依据。方法:收集从2013年10月至2015年12月期间在新疆维吾尔自治区维吾尔医医院接受住院治疗的660例膝骨性关节炎患者根据维吾尔医症候分型分为石膏状黏液质型OA组、涩味黏液质型OA组和异常黑胆质型OA组,并检测其血清胱抑素-C水平,将阳性三组进行两两比较。结果:纳入调查的有效病例660例。男性113例(17.1%)、女性547例(82.9%),男女比例为1:4.84,平均年龄:59.89±10.98岁。OA患者血清胱抑素-C阳性率为57.6%(380/660),其中石膏状黏液质型OA患者阳性率为61.2%(167/273),涩味黏液质型OA患者阳性率为53.2%(115/216),异常黑胆质型OA患者阳性率为57.9%(99/171);男性阳性率63.7%(72/113),女性阳性率56.3%(308/547),阳性率患者不同性别间Cys-C水平没有显著性差异(p0.05)。OA阳性率患者中不同异常体液分型间Cys-C水平的差异有统计学意义(P0.05)。结论:认为Cys-C与维吾尔医膝骨性关节炎的症候分型有一定相关性,但这有待与其他更多相关指标的联合评价和进一步深入研究;这结果也证明了维吾尔医治疗中补肾原则的可行性。
[Abstract]:Objective: to study the changes of serum cystatin C in patients with knee osteoarthritis and its correlation with abnormal humoral classification of Uygur doctors, and to explore the early diagnosis of abnormal humoral classification of knee osteoarthritis in Uygur doctors. The role of disease surveillance and the classification of Uygur medical symptoms, Methods: from October 2013 to December 2015, 660 cases of knee osteoarthrosis treated in Xinjiang Uygur Autonomous region Uygur Medical Hospital were collected. According to the classification of Uygur medical symptoms, patients with inflammation were divided into gypsum mucinous OA group. The levels of serum cystatin C were measured in acerbity mucinous OA group and abnormal black bile type OA group. Results: 660 effective cases were included in the investigation. 113 cases were male and 547 cases were female. The ratio of male to female was 1: 4.84. The average age was 59.89 卤10.98 years old. The positive rate of cystatin C in OA patients was 57.6%. The positive rate of 61.2% of OA patients was 16.7 / 273%, that of patients with astringent mucinous type OA was 53.2%, that of patients with abnormal nigra type OA was 57.9% of 171%; that of men was 63.72%, that of women was 56.33%, that of women was 56.38% of 547%, and that there was no significant difference in Cys-C levels between different genders. There were significant differences in Cys-C levels among different abnormal humoral types in patients with positive rate of p0.05.Osteoarthritis of Uygur knee was correlated with Cys-C. But this needs to be evaluated jointly with other related indexes and further studied, which also proves the feasibility of the principle of tonifying kidney in Uygur medical treatment.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R29

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