温和灸对绝经综合征阴虚体质患者性激素水平、应激状态的影响

发布时间：2018-03-09 06:04

本文选题：温和灸　切入点：绝经综合征　出处：《中国中医基础医学杂志》2017年08期 　论文类型：期刊论文

【摘要】：目的:探讨温和灸对绝经综合征阴虚体质患者性激素水平、应激状态的影响。方法:将60例患者按随机数字表法分为艾灸组和谷维素组各30例,艾灸组采用温和灸,谷维素组服用谷维素,比较2组患者治疗前后Kupperman、HAMA评分及E2、FSH、LH、ACTH、CORT指标的变化。结果:艾灸组治疗后血清E2升高,Kupperman、HAMA、体质转化分、FSH、ACTH及CORT均较治疗前降低,与谷维素组比较差异有统计学意义。Kupperman评分的下降与FSH、CORT、ACTH水平降低呈正相关;阴虚体质改善与E2升高呈负相关,与CORT、ACTH水平降低呈正相关。结论:温和灸可降低阴虚体质患者FSH水平、提高E2含量,其作用机制与调整中枢的下丘脑-垂体-性腺轴和下丘脑-垂体-肾上腺轴有关,ACTH、CORT是绝经综合征阴虚体质患者较为敏感的激素指标。
[Abstract]:Objective: to investigate the effect of mild moxibustion on sex hormone level and stress state in patients with yin deficiency of menopausal syndrome. Methods: 60 patients were divided into moxibustion group and oryzanol group by random digital table. Moxibustion group was treated with mild moxibustion. The changes of Kuppermann Hama score and E2FSHLHH + ACTHCORT index before and after treatment in oryzanol group were compared. Results: after treatment, serum E2 was increased in the moxibustion group, and the constitution transformation scores, FSH, ACTH and CORT were lower than those before and after treatment, and the changes of serum E 2 in the moxibustion group were lower than those in the control group before and after treatment, and the changes of serum E 2 in the moxibustion group were lower than those before and after treatment. Compared with oryzanol group, the decrease of Kupperman score was positively correlated with the decrease of FSHCORTACTH, and the improvement of Yin-deficiency constitution was negatively correlated with the increase of E2, and positively correlated with the decrease of Corton-ACTH. Conclusion: mild moxibustion can decrease the level of FSH in patients with Yin-deficiency constitution. The mechanism of increasing E _ 2 content is related to hypothalamus-pituitary-gonad axis and hypothalamus-pituitary-adrenal axis, which is a sensitive hormone index in postmenopausal syndrome patients with yin deficiency constitution.
【作者单位】：广西中医药大学第一附属医院仁爱分院;广西中医药大学研究生院;广西中医药大学第一附属医院针灸科;广西梧州市中医院针灸科;广西中医药大学第一附属医院检验科;广西壮族自治区人民医院星湖门诊部;
【基金】：广西科学研究与计划开发计划项目(桂科攻1140003B-59)-艾灸对阴虚和阳虚体质围绝经期患者的调养方案的研究
【分类号】：R246.3

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