基于胃癌相关微生态变化探讨“脾胃-肠”轴的交互作用

发布时间：2018-03-11 16:37

本文选题：胃癌　切入点：微生态　出处：《中华中医药杂志》2017年04期 　论文类型：期刊论文

【摘要】：肿瘤已成为目前威胁人类健康最主要的疾病之一,其中胃癌的发病率在某些地方已居于肿瘤的首位。目前,有研究认为胃癌的发病与肠道微生态紊乱有关,胃肠道微生态系统是维系小肠、大肠正常功能的核心要素和机体重要"功能器官",也是反映机体内环境稳定的"一面镜子"。反之,若肠道菌群异常及菌群移位与胃癌等肿瘤、糖尿病、多器官功能障碍综合征(MODS)及化疗、手术等重大创伤性疾病的发生发展密切相关。中医认为"脾胃互为表里""脾为后天之本""脾与小肠相关",故调控胃肠微生态平衡是中医药提高胃癌患者疗效的重要途径之一。
[Abstract]:Cancer has become one of the most important diseases threatening human health, in which the incidence of gastric cancer has been the highest in some places. At present, it is believed that the incidence of gastric cancer is related to intestinal microecological disorder. The gastrointestinal microecosystem is the core element of maintaining the normal function of the small intestine and large intestine and the important "functional organ" of the body. It is also a "mirror" reflecting the stability of the body's environment. Diabetes mellitus, multiple organ dysfunction syndrome (mods) and chemotherapy, The occurrence and development of major traumatic diseases such as surgery are closely related. Traditional Chinese medicine holds that "spleen and stomach are mutually internal", "spleen is acquired", "spleen and small intestine are related", so regulating gastrointestinal microecological balance is one of the important ways for TCM to improve the curative effect of gastric cancer patients.
【作者单位】：甘肃中医药大学甘肃省高校重大疾病分子医学与中医药防治研究省级重点实验室;敦煌医学与转化省部共建教育部重点实验室;
【分类号】：R273

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