轻度认知损害证候分布特征文献研究

发布时间：2018-03-11 17:06

本文选题：轻度认知损害　切入点：证候要素　出处：《中医杂志》2017年17期 　论文类型：期刊论文

【摘要】：目的探讨轻度认知损害的中医证候特征。方法检索1990年1月至2014年12月中国知网、万方数据库、维普数据库,收集轻度认知损害证候研究类文献,对其中中医证型及证候要素进行统计分析,使用SPSS 17.0软件进行聚类分析并结合专家经验得出各证候要素的相关症状。结果共纳入32篇文献,经术语规范化后得出轻度认知损害有24个证型,出现频次前5位的分别为痰浊蒙窍证、肾精亏虚证、气血两虚证、热毒内盛证、瘀阻脑络证。病位类证候要素中肾和脑所占比率最高,分别为30.83%和30.00%;病因、病性类证候要素中气虚所占比率最高为16.50%。根据聚类分析结果并结合专家经验共提取出15个证候要素,其中包含69个症状。结论轻度认知损害中医证型以痰浊蒙窍证与肾精亏虚证为主,病位主要在肾、脑,病性为气虚。
[Abstract]:Objective to explore the characteristics of TCM syndromes of mild cognitive impairment (MCI). Methods to search the literature on mild cognitive impairment in China from January 1990 to December 2014. The syndromes of TCM syndromes and syndromes were statistically analyzed, the cluster analysis was carried out with SPSS 17.0 software, and the related symptoms of each syndromes were obtained by combining with the experience of experts. After standardization of terminology, it was concluded that there were 24 types of mild cognitive impairment, and the first five types of occurrence frequency were phlegm turbid and resuscitation syndrome, kidney essence deficiency syndrome, qi and blood deficiency syndrome, heat toxin internal flourishing syndrome, respectively. The proportion of kidney and brain were 30.83% and 30.000.The proportion of Qi deficiency in etiology and disease syndromes was 16.50.The 15 syndromes were extracted according to the results of cluster analysis and expert experience. Conclusion the main types of mild cognitive impairment in TCM are phlegm turbid resuscitation syndrome and kidney essence deficiency syndrome.
【作者单位】：北京中医药大学研究生院;北京中医药大学东直门医院;中国中医科学院望京医院;
【基金】：北京市科技计划(Z151100003815021) 北京市中医药“十病十药”成药性研究(CYX2014-10)
【分类号】：R277.7

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