失眠伴肠道功能异常的临床初步观察

发布时间：2018-03-14 00:48

本文选题：失眠　切入点：肠道功能异常　出处：《中国中医基础医学杂志》2017年08期 　论文类型：期刊论文

【摘要】：目的:通过分析失眠伴肠道功能异常患者的临床特点及证候分布特征,研究失眠与肠道功能异常的关系。方法:采用横断面调查方法对238例失眠患者进行包括临床症状、PSQI评分、HAMA评分等系统分析,对肠道功能正常与肠道功能异常2组进行比较分析,其中肠道功能异常主要以排便异常为主。结果:238例失眠患者中,伴有排便异常患者占50.4%,排便异常主要分大便干、大便黏滞不爽、大便泄泻几种类型,失眠患者以中青年女性为多,主要从事脑力劳动,大多数性格急躁易怒、思虑过多。失眠伴有排便异常患者的焦虑程度偏高,临床以心烦、腰膝酸软、畏寒、口燥咽干、五心烦热、脱发、发变白、脘闷食少、腹胀、口黏不爽、纳食不消、咽中异物感、疲乏无力、边有齿痕、舌苔厚等症状为特征性临床表征。通过对失眠伴有肠道功能异常患者的敏感性和特异性临床表征进行聚类分析,发现失眠伴肠道功能异常患者以肝郁脾虚、郁而化火、湿浊困阻为核心证候病机。结论:失眠患者中焦虑程度偏高的容易出现肠道功能异常,失眠伴肠道功能异常患者以肝郁脾虚、郁而化火、湿浊困阻为核心证候病机。且失眠与肠道功能异常存在一定相关性,根据脑肠轴的存在推测脑与肠存在一定的关联,有待进一步临床研究证实。
[Abstract]:Objective: to analyze the clinical characteristics and syndromes distribution of insomnia patients with abnormal intestinal function. To study the relationship between insomnia and intestinal dysfunction. Methods: 238 patients with insomnia were analyzed systematically including clinical symptoms and PSQI score and Hama score. The normal intestinal function and abnormal intestinal function were compared between the two groups. Results of 238 patients with insomnia, 50.4 were accompanied by abnormal defecation. The abnormal defecation was mainly divided into dry stool, sticky defecation, diarrhea and several types of defecation. Most insomnia patients are young and middle-aged women, mainly engaged in mental work. Most of them are impatient and irritable, thinking too much. Patients with insomnia accompanied by abnormal defecation have a high degree of anxiety, clinical symptoms are upset, the waist and knee are sore, cold, and the mouth is dry. Five upset heat, hair loss, white hair, stomach-stuffy food less, abdominal distension, mouth sticky, food, pharynx foreign body feeling, fatigue, edge teeth marks, By cluster analysis of the sensitivity and specificity of the patients with insomnia accompanied with intestinal dysfunction, it was found that the patients with insomnia accompanied with abnormal intestinal function were characterized by liver depression and spleen deficiency. Conclusion: the patients with insomnia with high degree of anxiety are prone to abnormal intestinal function, and the patients with insomnia associated with abnormal intestinal function are characterized by liver depression and spleen deficiency, and the depression of fire. Dampness and turbid obstruction are the core syndromes, and insomnia has certain correlation with intestinal dysfunction. According to the existence of brain intestinal axis, it is inferred that there is a certain connection between brain and intestine, which needs further clinical research to prove.
【作者单位】：北京中医药大学;北京中医药大学东直门医院;太原市中医医院;
【分类号】：R256.23

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