海藻玉壶汤加味联合火针治疗结节囊肿性痤疮的临床疗效观察

发布时间：2018-03-20 03:15

本文选题：结节囊肿性痤疮　切入点：海藻玉壶汤加味　出处：《成都中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：本研究通过观察海藻玉壶汤加味联合火针治疗结节囊肿性痤疮的临床疗效和安全性,分析此疗法的作用机理,探讨其对于结节囊肿性痤疮的实用性,为临床应用提供参考依据。方法：采用随机分配入组的方法,所选的符合纳入标准的66例患者均于2015年2月到2015年12月期间在成都中医药大学附属医院皮肤科门诊就诊,随机分为治疗组33人,予海藻玉壶汤加味联合火针治疗；对照组33人,予异维A酸胶丸联合火针治疗。疗程为四周。用SPSS19.0统计学软件对两组患者治疗前后的症状体征量化评分和中医证候积分进行统计分析,从而做出疗效及安全性评价。并在治疗结束后随访观察两组愈显患者的复发率。结果：(1)治疗结束后,治疗组和对照组的症状体征疗效相比,两组的总有效率分别为84.4%和62.1%,经统计学比较有显著差异。(2)治疗结束后,两组中医证候的总体疗效比较,总有效率分别为81.3%、31.0%,两组在对于中医证候的治疗方面有统计学的差异。(3)两组在试验过程中均有轻微的不良反应,两组患者发生不良反应的对比为P0.05,治疗组较对照组的治疗方法更为安全。(4)两组患者在治疗结束后随访得到的复发数据比较,两组治疗疗效的稳定性相当。结论：海藻玉壶汤加味联合火针治疗结节囊肿性痤疮的疗效优于异维A酸胶丸联合火针的治法,对该病的治疗安全有效。
[Abstract]:Objective: to observe the clinical efficacy and safety of the treatment of nodular cystic acne with seaweed Yutong decoction and fire needle, and to analyze the mechanism of the treatment and to explore the practicability of the therapy for nodular cystic acne. Methods: 66 patients who met the inclusion criteria were selected from February 2015 to December 2015 in the Department of Dermatology, affiliated Hospital of Chengdu University of traditional Chinese Medicine. They were randomly divided into treatment group (n = 33) and control group (n = 33). The patients in the two groups were treated with isotinic acid gel pill and fire needle for four weeks. The quantitative score of symptoms and signs and the score of TCM syndromes before and after treatment were statistically analyzed by SPSS19.0 software. After the treatment, the recurrence rate of the two groups was observed. Results after the treatment, the symptoms and signs of the treatment group were compared with those of the control group. The total effective rates of the two groups were 84.4% and 62.1, respectively. There was a significant difference between the two groups after the treatment. The total effective rate was 81.3% and 31.0% respectively. There was a statistical difference between the two groups in the treatment of TCM syndromes. The adverse reactions of the two groups were compared to that of the control group (P0.05, the treatment group was safer than the control group). Conclusion: the curative effect of the two groups is better than that of isoretinoic acid pill combined with fire acupuncture, and it is safe and effective in the treatment of the disease.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R275.9

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