加味五子衍宗丸治疗肾气亏虚型尿频病的临床观察

发布时间：2018-03-24 01:15

本文选题：加味五子衍宗丸　切入点：尿频病　出处：《山东中医药大学》2016年硕士论文

【摘要】：目的:通过临床研究观察加味五子衍宗丸治疗肾气亏虚型尿频病的临床有效性和安全性,为肾气亏虚型尿频病的治疗提供新思路。方法:将符合纳入标准的60例尿频病患者,随机分为试验组、对照组各30例,在一般治疗的基础上,试验组给予加味五子衍宗丸免煎颗粒,日一剂;对照组给予酒石酸托特罗定片2mg,日2次。治疗28天,观察两组中医单项症状积分、国际下尿路症状(LUTS)评分、24h平均排尿次数、每日平均每次排尿量及不良反应等。结果:(1)两组单项症状积分比较:在尿频上试验组优于对照组,但差异性不显著(P0.05),在尿急、尿痛、畏寒肢冷、精神萎靡、腰膝酸软、尿后滴沥上试验组明显优于对照组(P0.01);(2)两组中医证候疗效比较:试验组总有效率90.00%,对照组总有效率53.33%,试验组明显优于对照组(P0.01);(3)治疗后试验组在LUTS评分、24h平均排尿次数和24h平均每次排尿量改善方面明显优于对照组(P0.01);(4)两组总有效率比较:试验组为86.67%,对照组66.67%,试验组优于对照组(P0.05)。结论:加味五子衍宗丸能有效改善肾气亏虚型尿频病患者的临床症状,其临床疗效优于常规西药,且安全性良好。可作为治疗肾气亏虚型尿频病的优化方案。
[Abstract]:Objective: to observe the clinical efficacy and safety of Jiawei Wuzi Yanzong Pill in the treatment of frequent urethritis with deficiency of Kidney Qi and deficiency of Kidney Qi, and to provide a new idea for the treatment of frequent urinary disease of deficiency of Kidney Qi. The experimental group was randomly divided into two groups: the control group (n = 30) and the control group (n = 30). On the basis of general treatment, the experimental group was treated with Jiawei Wuzi Yanzong pill for 28 days, and the control group with tolterodine tartrate tablets 2 mg per day for 28 days. Observe the score of single symptom of TCM, the score of international lower urinary tract symptom (LUTS) in 24 hours, the average amount of urination per day and the adverse reaction, etc. Results the comparison of single symptom score of two groups: the test group was superior to the control group in the frequency of urination. But the difference was not significant (P 0.05), in urination, urination pain, cold cold limbs, weak spirit, weak waist and knee, Comparison of the curative effect of TCM Syndrome between the two groups: the total effective rate of the test group was 90.00, the total effective rate of the control group was 53.33cm, and the test group was obviously superior to the control group (P0.01P0.01) after treatment, the average urination rate of the test group was 24 hours after the treatment. The total effective rate of the two groups was 86.67, 66.67 and 66.67, respectively. The experimental group was superior to the control group (P 0.05). Conclusion: the modified Wuzi Yanzong pill can effectively improve the urine of deficiency of kidney qi. The clinical symptoms of patients with frequent diseases, Its clinical efficacy is superior to that of conventional western medicine, and its safety is good. It can be used as an optimized scheme for the treatment of kidney qi deficiency.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.5

【相似文献】