加味四妙散内服合金黄膏外敷对急性痛风性关节炎的疗效及镇痛作用

发布时间：2018-03-24 06:27

本文选题：加味四妙散　切入点：金黄膏　出处：《中国中医急症》2017年03期

【摘要】：目的观察加味四妙散内服合金黄膏外敷治疗急性痛风性关节炎(AGA)的临床效果。方法将134例AGA患者按随机数字表法均分为两组。对照组给予常规西药治疗;观察组采取加味四妙散内服合金黄膏外敷治疗。记录比较两组治疗前后关节活动功能、压痛、肿胀及疼痛评分,疗程结束后临床疗效,治疗前后C反应蛋白(CRP)、红细胞沉降率(ESR)、白细胞介素-8(IL-8)、血尿酸(BUA)水平以及治疗期间不良反应。结果两组治疗后关节活动功能、压痛、肿胀及疼痛评分与治疗前比较,均显著降低(P0.01),且观察组症状改善程度较对照组相比,均更为显著(P0.01);观察组总有效率为94.03%,高于对照组的82.09%(P0.05);与治疗前比较,治疗后两组CRP、ESR、IL-8及BUA水平均显著改善(P0.01),且观察组改善幅度均更为显著(P0.01);观察组不良反应率为2.99%,明显低于对照组的13.43%(P0.05)。结论 AGA应用加味四妙散内服合金黄膏外敷治疗更能有效解除患者症状,镇痛效果更佳,疗效切实,安全可靠,具有较高临床参考价值。
[Abstract]:Objective to observe the clinical effect of Jiawei Simiao Powder on acute gouty arthritis (AGA). Methods 134 patients with AGA were divided into two groups according to random digital table. The control group was treated with routine western medicine. The observation group was treated by adding modified Simiao powder and taking alloy yellow ointment externally. The joint motion function, tenderness, swelling and pain scores were recorded and compared before and after treatment, and the clinical efficacy after the course of treatment was compared. Before and after treatment, the levels of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), interleukin-8 (IL-8U), serum uric acid (BUAA) and adverse reactions during the treatment were compared between the two groups in terms of joint activity, tenderness, swelling and pain scores before and after treatment. The total effective rate of the observation group was 94.03, which was higher than that of the control group (82.09 and 82.09), compared with that of the control group, the improvement degree of symptoms in the observation group was significantly higher than that in the control group, and the total effective rate of the observation group was 94.03, which was higher than that of the control group (P 0.05). After treatment, the levels of IL-8 and BUA were significantly improved in the two groups, and the range of improvement in the observation group was more significant than that in the observation group, and the adverse reaction rate in the observation group was 2.99, which was significantly lower than that in the control group. Conclusion AGA was treated with Jiawei Simiao Powder and taking Yaohuang Ointment externally. It is more effective in relieving the symptoms of the patients. The analgesia effect is better, the curative effect is practical, the safety is reliable, has the high clinical reference value.
【作者单位】：湖北省恩施土家族苗族自治州中心医院;
【基金】：恩施土家族苗族自治州卫生计生委硒与人体健康科研项目资助(201567017)
【分类号】：R259

【相似文献】