穴位贴敷配合中药治疗气滞血瘀型盆腔炎性疾病后遗症的临床研究

发布时间：2018-03-24 11:43

本文选题：穴位贴敷　切入点：盆腔炎性疾病后遗症　出处：《南京中医药大学》2017年硕士论文

【摘要】：目的:通过观察中医外治法穴位贴敷配合中药口服的联合治疗方法,以及仅仅单纯口服中药疗法,总结分析两种方式治疗气滞血瘀型盆腔炎性疾病后遗症的临床疗效差异,总结穴位贴敷在治疗盆腔炎性疾病后遗症时发挥的临床意义,并探讨其作用机制,寻找最佳治疗方案,体现中医药特色外治疗法的优势,以进一步提高治愈率与远期疗效、缩短疗程、降低复发率、减少患者的痛苦,为临床推广应用提供依据。方法:采用随机、平行对照原则,纳入符合标准患者44例,分为治疗组及对照组。治疗组予穴位贴敷配合中药汤剂盆腔炎方口服,对照组则仅予中药汤剂盆腔炎方口服治疗。两组患者治疗周期均3个月,分别记录治疗前后的症状体征评分、盆腔血流动力学变化及炎症因子白介素-8(IL-8)的变化,通过比较两组治疗前后检查结果,评估两种治疗方式的效果差异。结果:(1)两组患者治疗前后综合疗效、综合、症状、体征积分经统计学分析均具有显著性差异(P0.05)(2)①治疗组患者治疗后子宫左右侧动脉搏动指数、阻力指数及子宫右侧动脉最大流速,经统计具有统计学意义(P0.05)②治疗组治疗后子宫左侧动脉的最大流速无明显差异(P0.05)。③对照组治疗后子宫左右侧动脉搏动指数、阻力指数、最大流速差异无统计学意义(P0.05)。(3)①治疗组与对照组治疗前后血清中IL-8值相比,均有统计学差异(P0.05)。②治疗组与对照组治疗后血清中IL-8值相比,有统计学差异(P0.05)。结论:中药汤剂口服及穴位贴敷疗法均能改善盆腔炎性疾病后遗症患者的症状及体征,但两者配合治疗的效果明显优于单纯中药口服治疗,联合疗法也能更好的改善盆腔血流动力学,改善IL-8在血清中的表达,证明穴位贴敷作为中医特色外治法,配合中药汤剂口服的联合疗法治疗气滞血瘀型盆腔炎性疾病后遗症效果明显优于单纯中药疗法,应当为临床广泛运用。
[Abstract]:Objective: to observe the combined therapy of acupoint application and oral administration of traditional Chinese medicine, and to summarize and analyze the difference of clinical curative effect between the two methods in treating the sequelae of pelvic inflammatory disease of qi stagnation and blood stasis type. To summarize the clinical significance of acupoint application in the treatment of the sequelae of pelvic inflammatory disease, to explore its mechanism, to find the best treatment scheme and to reflect the advantages of external treatment with Chinese medicine, so as to further improve the cure rate and long-term curative effect. To shorten the course of treatment, reduce the recurrence rate, reduce the pain of the patients, and provide the basis for clinical application. The treatment group was divided into treatment group and control group. The treatment group was treated with acupoint application combined with traditional Chinese medicine decoction pelvic inflammatory prescription, while the control group was only treated with traditional Chinese medicine decoction pelvic inflammatory prescription. The treatment period of both groups was 3 months. The scores of symptoms and signs, the changes of pelvic hemodynamics and the changes of interleukin-8 (IL-8) were recorded before and after treatment, and the results before and after treatment were compared between the two groups. Results there were significant differences in the scores of comprehensive curative effect, syntheses, symptoms and signs before and after treatment between the two groups. The pulsatility index of left and right uterine artery was significantly different in the treatment group (P 0.05). The resistance index and the maximum velocity of right uterine artery were statistically significant. There was no significant difference in the maximal velocity of left uterine artery after treatment in P0.05T-2 treatment group. The pulsatility index and resistance index of left and right uterine artery in control group were not significantly different after treatment. There was no significant difference in the maximum flow velocity between the two groups before and after treatment. There were significant differences in serum IL-8 levels between the two groups before and after treatment. There was also significant difference between the treatment group and the control group in the serum IL-8 levels after treatment. Conclusion: both oral Chinese medicine decoction and acupoint application therapy can improve the symptoms and signs of patients with pelvic inflammatory disease sequelae, but the effect of combined treatment is obviously better than that of traditional Chinese medicine alone. The combination therapy can also improve the pelvic hemodynamics, improve the expression of IL-8 in serum, prove that acupoint application is the characteristic external therapy of traditional Chinese medicine. The combined therapy combined with traditional Chinese medicine decoction in treating the sequelae of Qi stagnation and Blood stasis type pelvic inflammatory disease is obviously better than that of traditional Chinese medicine alone, and should be widely used in clinical practice.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R271.9

【参考文献】