原发性血小板增多症的中医证素初探

发布时间：2018-03-24 22:45

本文选题：原发性血小板增多症　切入点：证素　出处：《南京中医药大学》2016年硕士论文

【摘要】：目的：统计分析临床原发性血小板增多症(essential thrombocythemia, ET)患者的证候,进行证素评分,探讨各证素的分布特点,以期为ET的中医辨证论治提供新的思路和方法。方法：对84例明确诊断ET且符合纳入标准的患者进行相关证候采集,然后应用证素积分方法,统计分析出ET相关主要证素,并从性别、年龄、危险分层等角度进行差异性比较。结果：根据ET主要证素积分的统计和分析,概述如下：1.ET的主要证素分布情况：病位以肝为主要证素,脾、肾次之,累及经络、心神等；病性证素：阴虚、血瘀、气虚、气滞的证素积分最高,血虚、阳亢、阳虚次之,涉及寒、湿、热等。此外,未绝经的女性患者,胞宫在病位证素中有重要意义。2.从性别角度进行证素比较：男、女组进行病位证素比较未见明显差异；病性证素分析显示,女性患者血瘀征象较男性患者明显,且机体更容易受寒、湿的影响。3.从各年龄段分析：各年龄段主要病位证素都为肝,且无明显差异；中、老年患者其脾、肾二脏功能失调较年轻患者明显,累及心神、经络出现相关症状更明显。从病性看,高年龄段更阳虚、气虚、血虚更明显,低年龄段气滞、阳亢、阴虚更明显。4.高危、低危组证素积分比较结果示：高危组ET患者病位累及脾、肾、心神、经络较低危组更明显,气滞、血瘀、气虚、阳虚、血虚等相关征象也较低危组明显；而阳亢、阴虚相关表现多在低危组出现。结论：ET病位主要在肝,累及脾、肾,对心神、经络、胞宫(女性)的结构和功能有较大影响：ET的病因病机多为虚实夹杂,以气虚、阴虚为本虚,气滞、血瘀为标实,久病兼夹阳虚、血虚表现。女性患者瘀象较男性明显；高危及老年患者虚损征象明显,临床在活血化瘀祛邪的同时更应重视扶正固本。
[Abstract]:Objective: to analyze the syndromes of patients with essential thrombocytopenia (et), to evaluate the syndromes, and to explore the distribution characteristics of the syndromes in patients with essential thrombocytopenia (et). Methods: 84 patients with et who met the inclusion criteria were collected with relevant syndromes, and then the main syndromes of et were statistically analyzed by using the integral method of syndromes. Results: according to the statistics and analysis of et's main syndromes, the distribution of et's main syndromes was summarized as follows: liver was the main syndromes, spleen and kidney were the second. Involving the meridians, the heart and the mind, the factors of disease syndrome: yin deficiency, blood stasis, qi deficiency, qi stagnation, the highest score of syndromes, blood deficiency, hyperactivity of yang, yang deficiency, and so on. In addition, women with unmenopausal women are involved in cold, dampness, heat, etc. There was no significant difference between male and female in the comparison of syndromes from the gender point of view, and the analysis of the factors of disease syndrome showed that the blood stasis sign of female patients was more obvious than that of male patients. And the body is more susceptible to cold and dampness. 3. Analysis from different ages: the main syndromes of all age groups are liver, and there is no significant difference; in middle and old patients, the dysfunction of spleen, kidney and viscera is more obvious than that of young patients, involving heart and mind. The symptoms related to meridians were more obvious. From the point of view of disease, the high age group had more yang deficiency, qi deficiency, blood deficiency more obvious, lower age group qi stagnation, yang hyperactivity, yin deficiency more obvious .4. high risk, The results showed that the disease position of et patients in high risk group involved spleen, kidney, heart and spirit, meridian and meridian were more obvious than those in low risk group, Qi stagnation, blood stasis, qi deficiency, yang deficiency, blood deficiency and other related signs were more obvious than those in low risk group, while hyperactivity of yang was more obvious than that of low risk group. Conclusions the disease position of 1: et is mainly in liver, spleen, kidney, the structure and function of heart and spirit, meridian and phratry (female). The etiology and pathogenesis of et is mostly composed of deficiency of qi and deficiency of yin, which is based on deficiency of qi and deficiency of yin, and it is mainly caused by deficiency of qi, deficiency of yin, deficiency of yin and deficiency of yin, which has great influence on the structure and function of the meridians and meridians. Qi stagnation, blood stasis as the standard solid, long illness and Yang deficiency, blood deficiency performance. Female patients with blood stasis is more obvious than men, high risk and elderly patients with deficiency signs are obvious, the clinical practice in promoting blood circulation to remove blood stasis and evil should pay more attention to strengthening and strengthening the root at the same time.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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