补肾滋血汤治疗月经过少肾虚证的临床研究

发布时间：2018-03-26 05:32

本文选题：月经过少　切入点：肾虚证　出处：《广西中医药大学》2016年硕士论文

【摘要】：目的:观察补肾滋血汤对月经过少患者经量的影响,研究补肾滋血汤治疗月经过少的临床效果。方法:本研究病例来自2014年1月至2015年12月期间,在广西中医药大学附属瑞康医院妇科门诊就诊的60例患者。符合月经过少肾虚证的诊断、辩证标准。病例随机分为观察组和对照组各30例。观察组给予补肾滋血汤,每日1付,水煎后分2次内服;对照组给予乌鸡白凤丸,每次1丸,1日2次温水送服,两组治疗3个月经周期后,随访3个月。观察患者月经量、色、质及行经时间的改善情况,以及临床症状、子宫内膜厚度、性激素、基础体温的改善情况,观察结果经spss20.0统计学软件分析后,判定两组药物的有效性和安全性。结果:1.两组对患者经量的影响:观察组治疗前后经量评分由20.60±6.19分上升至50.20±11.60分,对照组治疗前后经量评分由20.90±6.01分上升至42.87±13.49分,两组治疗前后比较,差异有统计学意义(p0.01),治疗后两组经量均有所增加。治疗后两组经量评分差值比较,差异有统计学意义(p0.05),观察组疗效优于对照组。两组治疗后随访经量改善的疗效比较,观察组治愈率为16.67%,显效率为46.67%,有效率为23.33%,总有效率为86.67%;对照组治愈率为3.33%,显效率为36.67%,有效率为30.00%,总有效率为70.00%,治疗后两组间比较,差异有统计学意义(p0.05),观察组疗效优于对照组。2.两组症状的改善情况:观察组治疗前后症状总积分由19.60±5.42下降至5.73±4.66,对照组治疗前后症状总积分由18.20±5.88下降至7.73±5.87,两组治疗前后比较,差异有统计学意义(p0.01)。治疗后两组症状总积分差值比较,差异有统计学意义(p0.01),观察组疗效优于对照组。3.两组对性激素、子宫内膜、基础体温的影响:两组改善子宫内膜厚度比较,差异均有统计学意义(p0.01),两组均可明显促进黄体中期的子宫内膜增生和修复。治疗后两组间比较,差异无统计学意义(p0.05),两组药物对黄体中期子宫内膜厚度的改善情况无明显差异。两组改善性激素情况比较,补肾滋血汤可轻微升高血清早卵泡期的FSH值和E值(p0.05)。对T、PRL、LH值均没有明显影响(p0.05)。乌鸡白凤丸对FSH、E、T、PRL、LH值均没有明显影响(p0.05)。两组药物对治疗前后BBT的改善情况均无明显影响(p0.05)。4.两组综合疗效比较:观察组治愈率为16.67%,显效率为33.33%,有效率为40.00%,总有效率为90.00%;对照组治愈率为3.34%,显效率为23.33%,有效率为50.00%,总有效率为76.67%,治疗后两组间比较,差异有统计学意义(p0.05),观察组疗效优于对照组。结论:补肾滋血汤治疗月经过少具有良好临床疗效。
[Abstract]:Objective: to observe the effect of Bushen Zixue decoction on menstrual insufficiency, and to study the clinical effect of Bushen Zixue decoction on menorrhagia. Methods: this study was conducted from January 2014 to December 2015. Sixty patients in the gynecological clinic of Ruikang Hospital affiliated to Guangxi University of traditional Chinese Medicine. According to the diagnosis and dialectical standard of deficiency of menstruation and kidney syndrome, the cases were randomly divided into observation group and control group, 30 cases each. The observation group was given Bushen Zixue decoction, 1 payment per day. The control group was given Wuji Baifeng pills (1 pill each time, 2 times a day with warm water). After 3 menstrual cycles, the two groups were followed up for 3 months. The improvement of menstrual volume, color, quality and menstrual time were observed. And the improvement of clinical symptoms, endometrial thickness, sex hormone and basic body temperature. The results were analyzed by spss20.0 statistical software. Results the effect of the two groups on the patients' dosages was determined. Results: before and after treatment, the menstrual volume score of the observation group increased from 20.60 卤6.19 to 50.20 卤11.60, and that of the control group increased from 20.90 卤6.01 to 42.87 卤13.49, and that of the control group increased from 20.90 卤6.01 to 42.87 卤13.49, and that of the control group increased from 20.90 卤6.01 to 42.87 卤13.49 before and after treatment. The difference between the two groups before and after treatment was statistically significant (p 0.01), and the volume of the two groups increased after treatment. The difference was statistically significant (P 0.05). The curative effect of the observation group was better than that of the control group. In the observation group, the cure rate was 16.67, the markedly effective rate was 46.67, the effective rate was 23.33 and the total effective rate was 86.67; in the control group, the cure rate was 3.33; the markedly effective rate was 36.67; the effective rate was 30.007; and the total effective rate was 70.00.After the treatment, the two groups were compared. The effect of observation group was better than that of control group. The symptom score of observation group decreased from 19.60 卤5.42 to 5.73 卤4.66 before and after treatment, and that of control group decreased from 18.20 卤5.88 to 7.73 卤5.87 before and after treatment. The difference was statistically significant (P 0.01). After treatment, the difference in the total score of symptoms between the two groups was statistically significant. The curative effect of the observation group was better than that of the control group .3.The effect of the two groups on sex hormone, endometrium and basic body temperature: the two groups improved the thickness of endometrium. The difference was statistically significant (P 0.01). Both groups could significantly promote endometrial hyperplasia and repair in the middle luteal phase. There was no significant difference in endometrial thickness between the two groups, and there was no significant difference between the two groups in improving the endometrial thickness in the middle luteal phase. Bushen Zixue decoction can slightly increase the FSH value and E value of serum early follicle phase (P 0.05). There is no significant effect on the serum FSH value and E value of Bushen Zixue decoction. There is no significant effect of Wuji Baifeng Pill on BBT before and after treatment. There is no significant effect of Wuji Baifeng Pill on BBT before and after treatment. Comparison between the two groups: the cure rate in the observation group was 16.67, the effective rate was 33.33, the effective rate was 40.003, the total effective rate was 90.00.The cure rate in the control group was 3.34, the effective rate was 23.33, the effective rate was 50.00,the total effective rate was 76.677.After the treatment, the two groups were compared. The difference was statistically significant (P 0.05). The curative effect of the observation group was better than that of the control group. Conclusion: Bushen Zixue decoction has good clinical effect in treating menorrhagia.
【学位授予单位】：广西中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.111

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