补益脾胃法治疗脾胃虚弱型慢性萎缩性胃炎的临床研究

发布时间：2018-03-26 11:05

  本文选题：慢性萎缩性胃炎　切入点：脾胃虚弱型　出处：《南京中医药大学》2017年硕士论文

【摘要】：目的:探讨脾胃虚弱型慢性萎缩性胃炎胃粘膜上皮病变的中医病机,观察临床疗效,旨在完善慢性萎缩性胃炎的诊治思路、为医患提供优选健康宣教方案。方法:系统回顾《内经》、《灵枢》、《伤寒论》、《金匮要略》、《难经》等医籍,挖掘胃粘膜上皮病变的中医病机,总结健康宣教要点。以临床符合纳入标准60例慢性萎缩性胃炎患者为研讨对象,按随机对照的原则分为治疗组及对照组,两组病例的基本情况、症状、体征、胃镜及病理等均无统计学差异。治疗组服用六君子汤化裁方,每日1剂,早晚饭后半小时分服,每次200ml;对照组予胃复春片饭前半小时口服,一次4片,一日3次。一个疗程为6个月,服药1个疗程后复查胃镜及病理,对患者治疗前后的症状、体征、胃镜、病理进行统计学分析,判断治疗效果。结果:补益脾胃法的治疗组在改善症状、胃镜及病理分级疗效上均优于对照。结论:补益脾胃法治疗脾胃虚弱型慢性萎缩性胃炎不仅可改善临床症状,而且可改善明显内镜下粘膜及病理组织学形态。
[Abstract]:Objective: to investigate the pathogenesis of chronic atrophic gastritis of spleen and stomach, observe the clinical effect and improve the diagnosis and treatment of chronic atrophic gastritis. Methods: a systematic review of the medical books such as Internal Classic >, Lingshu >, Treatise on febrile Disease, synopsis of Golden Chamber and difficult Sutra was carried out to excavate the pathogenesis of gastric mucosal epithelial lesions. The main points of health education were summarized. 60 patients with chronic atrophic gastritis were divided into treatment group and control group according to the principle of random control. There was no statistical difference in gastroscopy and pathology. The treatment group was treated with Liujunzi decoction, 1 dose per day, 200 ml in the morning and evening half an hour after the meal, while the control group was given orally half an hour before the meal, 4 tablets once a day, the control group was treated with Weifuchun tablet half an hour before the meal. Three times a day. The course of treatment was 6 months. After one course of treatment, the symptoms, signs, endoscopy and pathology of the patients before and after treatment were analyzed statistically. Results: the treatment group of tonifying spleen and stomach was superior to the control group in improving symptoms, gastroscopy and pathological grading. Conclusion: tonifying spleen and stomach can not only improve the clinical symptoms of chronic atrophic gastritis with asthenia of spleen and stomach, but also improve the clinical symptoms of chronic atrophic gastritis. Moreover, it can improve the mucosal and histopathologic morphology under endoscope.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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