复元饮对THA术后隐性及快速康复的影响

发布时间：2018-03-26 17:10

本文选题：复元饮　切入点：全髋关节置换术　出处：《时珍国医国药》2017年09期

【摘要】：目的探讨复元饮联合局部氨甲环酸(TXA)对全髋关节置换(THA)术后隐性失血及快速康复的影响。方法采用随机数字表法将124例拟行全髋关节置换术患者随机分为两组:试验组62例,术前2 d及术后6 h后口服我院中药制剂复元饮;对照组62例,于术前30 min静滴TXA 1 g;两组患者术中均局部使用TXA 1g。观察并比较两组患者术前、术后第1、3、7天血红蛋白值(HB)、红细胞比容(HCT)值;术中出血量、术后引流量、术后第1、3、7天隐性失血量;整体康复评分;不良事件包括输血率、深静脉血栓形成(DVT)、肺栓塞(PE)发生率。结果两组显性失血及术后隐性失血量相近,差异均无统计学意义(P0.05),但试验组的输血率、DVT发生率更低,且整体康复评分更优,差异均有统计学意义(P0.05)。结论复元饮联合术中局部使用TXA能有效控制全髋关节置换术后隐性失血,降低输血率,减少DVT发生率,且能促进患者早期整体康复,值得临床应用。
[Abstract]:Objective to investigate the effect of Fuyuan Yin combined with local aminoformic acid (TXA) on recessive blood loss and rapid recovery after total hip replacement. Methods 124 patients with total hip replacement were randomly divided into two groups: experimental group (n = 62), total hip replacement (THA) group (n = 62), total hip replacement (THA) group (n = 62) and total hip replacement (THA) group (n = 62). Two days before operation and 6 hours after operation, Fuyuan Yin, a traditional Chinese medicine preparation, was taken orally in our hospital; in the control group, 62 cases were given intravenous drip of TXA 1 g 30 min before operation. The patients in both groups were given TXA 1g locally during operation. The hemoglobin value and HCT value on the 1st day and 3rd day after operation, the volume of blood loss during operation, the volume of drainage after operation, the amount of recessive blood loss on the 1st day and the 7th day after operation, the overall rehabilitation score, the adverse events including the rate of blood transfusion, Results there was no significant difference between the two groups in the amount of dominant blood loss and recessive blood loss after operation, but the rate of blood transfusion and DVT in the trial group was lower than that in the control group, and the overall rehabilitation score was better than that in the control group, and there was no significant difference between the two groups in the incidence of DVT and PE.Results there was no significant difference between the two groups. Conclusion Fuyuan Yin combined with local use of TXA during operation can effectively control recessive blood loss after total hip arthroplasty, reduce blood transfusion rate, reduce the incidence of DVT, and promote the early recovery of patients, which is worthy of clinical application.
【作者单位】：广州中医药大学附属佛山中医院;广东省佛山市第二人民医院;
【基金】：广东省佛山市卫生和计生局医学科研课题(No.20170092)
【分类号】：R274.9

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