化痰贴方对社区获得性肺炎（痰热壅肺证）的疗效观察

发布时间：2018-03-29 04:17

本文选题：社区获得性肺炎　切入点：化痰贴方　出处：《广州中医药大学》2016年硕士论文

【摘要】：目的：通过观察化痰贴方对社区获得性肺炎(痰热壅肺证)患者的临床症状改善情况、炎症指标变化情况、胸部CT变化情况等,以了解其在社区获得性肺炎痰热壅肺证患者中的疗效,以期指导临床应用及社会推广。方法：本课题运用前瞻性单盲随机对照的研究方法。一共收集满足研究标准的病人83例,随机成两组,其中治疗组43例,对照组40例,两组都给以相同的西医基础治疗,治疗组加上化痰贴方,对照组加上安慰剂,疗程都为7天,观察病人的症状、WBC、 CRP、PCT和胸部CT的变化。通过统计来比较两组的疗效,以客观评价化痰贴方治疗本病的效果。结果：1.两组在治疗第3天、第5天、第7天时与治疗前的咳嗽、咯痰积分差值进行独立样本t检验,P0.05,均有显著性差异。2.两组治疗前后WBC经配对t检验,P0.05,均有显著性差异；两组治疗后WBC经独立样本t检验,P0.05,无显著性差异。3.两组治疗前后血清CRP值行配对t检验,P0.05,均有显著性差异；两组治疗后血清CRP数值行独立样本t检验,P0.05,无显著性差异。3.两组治疗前后PCT值行t配对检验,P0.05,均有显著性差异；两组治疗后血PCT数值行配对t检验,P0.05,无显著性差异。4.两组治疗后胸部CT的改变予秩和检验,P0.05,有显著性差异。结论：1.同对照组相比,治疗组的病人咯痰(包括痰色、痰量、痰质)和咳嗽(包括发作持续时间、咳嗽的剧烈程度)症状缓解速度较快,说明化痰贴方能较好地缓解病人的症状,减轻他们的痛苦。2.治疗组在减轻肺热病痰热壅肺证患者的炎症指标方面无明显优势。但在胸部CT渗出影的消散方面,治疗组有明显的优势。所以可以得出化痰贴方配合西医治疗肺炎痰热壅肺证,同单纯西医疗法相比,可以更好地缓解病患的痛苦,充分体现了中医药自身的独特优势。
[Abstract]:Objective: to observe the improvement of clinical symptoms, changes of inflammatory indexes and CT changes of chest in patients with community-acquired pneumonia (syndrome of phlegm-heat obstruction of lung) treated with Huatan paste. In order to understand its curative effect in community acquired pneumonia patients with phlegm heat obstruction of lung syndrome, in order to guide clinical application and social popularization. Methods: this study used a prospective single-blind randomized control study method. A total of 83 patients who met the criteria of the study were collected. They were randomly divided into two groups: the treatment group (43 cases) and the control group (40 cases). Both groups were given the same basic western medicine treatment, the treatment group plus Huatan paste, the control group plus placebo, the course of treatment was 7 days. To compare the curative effect of the two groups by statistics, and to evaluate objectively the effect of Huatan plaster on the treatment of this disease. Results: the two groups had cough on the 3rd, 5th, 7th day after treatment. The difference of sputum integral between the two groups was significantly different (P 0.05) after the treatment. There was significant difference between the two groups before and after treatment by paired t test (P 0.05). There was no significant difference in WBC between the two groups after treatment by independent t-test (P0.05). There was no significant difference between the two groups before and after treatment. The serum CRP values of the two groups were matched with t-test (P0.05), and there was significant difference between the two groups before and after treatment. After treatment, the serum CRP values of the two groups were tested by independent sample t-test (P0.05), but there was no significant difference between the two groups. The PCT values of the two groups were tested with t-pairing test (P0.05) before and after treatment, and there was significant difference between the two groups. There was no significant difference between the two groups in PCT values after treatment. There was no significant difference between the two groups in chest CT changes after treatment (P 0.05). Conclusion: 1. Compared with the control group, the patients in the treatment group had sputum (including sputum color, sputum volume). Symptoms of cough (including duration of onset, severity of cough) were relieved faster, indicating that Huatan plaster could better relieve the symptoms of patients. 2. The treatment group has no obvious advantage in reducing the inflammatory indexes of the patients with phlegm and heat obstruction of lung fever. However, it has no obvious advantage in the dissipation of chest CT exudation. The treatment group has obvious advantages. So it can be concluded that Huatan paste prescription combined with western medicine in the treatment of pneumonia phlegm heat obstruction lung syndrome, compared with simple Western medicine therapy, can better alleviate the pain of patients, fully reflect the unique advantages of TCM itself.
【学位授予单位】：广州中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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