柏硝祛毒洗剂对防治肛裂术后并发症的临床观察

发布时间：2018-03-29 07:07

本文选题：柏硝祛毒洗剂　切入点：肛裂　出处：《华北理工大学》2016年硕士论文

【摘要】：目的观察柏硝祛毒洗剂熏洗用于肛裂术后的临床表现,通过比较患者术后疼痛、水肿、出血、创面愈合以及抑菌的评分差异,证实柏硝祛毒洗剂防治肛裂术后常见并发症的临床疗效。方法选取符合标准的120例肛裂患者,随机分为治疗组(柏硝祛毒洗剂)和对照组(金玄痔科熏洗液),两组患者术前以及术后常规治疗一致,并对术前两组的性别、病程、年龄以及术后的切口数目、术后当天的疼痛、水肿、出血的症状评分和术后当天创面的面积经进行比较,判断两组是否具有可比性。肛裂术后,治疗组以100ml柏硝祛毒洗剂兑900ml温水熏洗,对照组予金玄痔科熏洗散兑1000ml温水熏洗,55g/次,并控制两组保持相同的熏洗时间与温度。对术后的疼痛、水肿、出血进行症状量化评分,并分别记录两组术后用药0、3、6、9d的症状评分以及创面愈合面积、创面愈合率以及创面愈合的时间;于术后用药3、6、9d换药时取患者创面少许分泌物进行抑菌实验,测量抑菌环直径,对抑菌环直径进行评分,并记录两组患者治疗后的总体疗效和治疗期间患者的不良反应,以统计学分析处理进行比较。结果两组术前的性别、病程、年龄,以及术后的切口数目、术后当天的疼痛、水肿、出血的症状评分和术后当天创面的面积的比较,P0.05,差异无统计学意义,具有可比性。两组术后用药3、6、9d的疼痛、水肿、出血的评分以及创面愈合面积、创面愈合率较术后当天比较,P0.05,差异具有统计学意义;且治疗组优于照组,P0.05。两组术后用药3、6、9d的抑菌评分较术后当天比较,P0.05;且治疗组优于照组,P0.05。两组术后创面愈合时间及术后用药21d总疗效比较,P0.05。治疗期间,治疗组10名患者见肛门瘙痒,对照组13名患者见肛门瘙痒,无特殊处理后症状好转,未对本次研究产生影响,两组均未见其他不良反应。结论1柏硝祛毒洗剂熏洗用于肛裂术后,可明显减轻术疼痛、水肿、出血症状,并能促进伤口愈合,缩短伤口愈合时间。2柏硝祛毒洗剂熏洗对肛裂术后伤口抑菌效果显著,可防治伤口感染,安全有效,适宜临床推广。
[Abstract]:Objective to observe the clinical manifestations after anal fissure treated by fumigation and washing with antidoxide lotion, and to compare the scores of pain, edema, bleeding, wound healing and bacteriostasis after operation in patients with anal fissure. Methods 120 patients with anal fissure were selected. The two groups were randomly divided into two groups: the treatment group and the control group. The two groups had the same routine treatment before and after operation, and the gender, course of disease, age and the number of incisions after operation were the same in the two groups. The scores of pain, edema and bleeding on the day after operation were compared with the area of the wound on the day after operation. After anal fissure operation, the treatment group was fumigated with 100ml antitoxic lotion and 900ml warm water. The control group was treated with Jinxuan hemorrhoids fumigation powder and 1000ml warm water fumigation washing powder 55g / time, and the control group maintained the same fumigation time and temperature. The symptom scores, wound healing area, wound healing rate and wound healing time of the two groups were recorded respectively, and a little secretion of the wound was taken from the patients for bacteriostasis test, and the diameter of the bacteriostasis ring was measured. The diameter of the bacteriostasis ring was evaluated, and the overall curative effect and adverse reactions during the treatment were recorded. Results the sex, course, age of the two groups before operation were compared by statistical analysis. There was no significant difference in the number of incisions, pain, edema, bleeding symptom score and wound area on the day of operation (P 0.05). There was no significant difference between the two groups, and there was no significant difference between the two groups. The score of bleeding, the area of wound healing and the rate of wound healing were significantly higher than those on the day of operation (P 0.05). The bacteriostasis score of the two groups was better than that of the control group (P 0.05), and that of the treatment group was better than that of the irradiation group (P 0.05). The healing time of the wound and the total curative effect of 21 days after treatment were compared between the two groups during the treatment period. In the treatment group, 10 patients had anal itching, while in the control group, 13 patients had anal itching. Conclusion 1 fumigation and washing with antidotal lotion for anal fissure can significantly relieve pain, edema, bleeding symptoms and promote wound healing after anal fissure. The time of wound healing was shortened. 2. Fumigation and washing with Bahnite dispel toxin lotion had obvious effect on bacteriostasis after anal fissure operation. It could prevent and cure wound infection, and was safe and effective. It was suitable for clinical application.
【学位授予单位】：华北理工大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R266

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