乌鲁木齐、伊犁两地区汉族心血管衰老规律差异及与西北燥证相关性研究

发布时间：2018-03-30 00:36

  本文选题：心血管衰老　切入点：西北燥证　出处：《新疆医科大学》2016年硕士论文

【摘要】：目的:探讨乌鲁木齐、伊犁两地区汉族心血管衰老规律及与西北燥证的相关关系,为新疆地区心血管衰老的防治提供理论依据。方法:从乌鲁木齐、伊犁两地区共筛选474例自我评价健康的汉族居民,采用现场调查、实验室检测、心脏彩超检查相结合的方法,比较乌鲁木齐、伊犁两地区汉族心血管衰老规律的差异,分析西北燥证与心血管衰老规律的相关关系。结果:(1)心血管衰老相关指标:1)血压指标:SBP、PP、PPI;2)肾功能指标:BUN、Cr、Cys C、ALBU;3)心脏彩超指标:AD、LA、LVDd、LVDs、RA、RV、PA、LVEF。(2)乌鲁木齐、伊犁两地区汉族心血管衰老相关指标中SBP、PP、PPI、BUN、Cr、Cys C、AD、LA、LVDd、LVDs、RA、RV、PA指标均随增龄逐渐上升,而ALBU、LVEF指标均随增龄逐渐下降,其中可以作为心血管衰老标志物的指标有:SBP、PP、BUN、Cys C、ALBU、LA、LVDd、LVDs、RV、LVEF。(3)乌鲁木齐、伊犁两地区汉族西北燥证罹患率均随增龄呈上升趋势,乌鲁木齐汉族西北燥证罹患率高于伊犁汉族(P0.05)。(4)相同年龄组,不同地区间比较:1)30-44岁组、45-59岁组:乌鲁木齐汉族心血管衰老进展较伊犁汉族为快,在这两个年龄组乌鲁木齐汉族西北燥证罹患率亦较伊犁汉族为高,其中45-59岁组两地区西北燥证罹患率比较差异有统计学意义(P0.05);2)60-74岁组:两地区汉族心血管衰老均迅速进展,伊犁汉族心血管衰老进展较乌鲁木齐汉族为快,该年龄组乌鲁木齐汉族西北燥证罹患率较伊犁汉族略高,但伊犁汉族西北燥证罹患率上升幅度明显大于乌鲁木齐汉族,60-74岁组两地区西北燥证罹患率比较差异无统计学意义(P0.05);3)≥75岁组:乌鲁木齐汉族心血管衰老进展较伊犁汉族略快,但伊犁汉族西北燥证罹患率较乌鲁木齐汉族略高,此年龄组两地区西北燥证罹患率比较差异无统计学意义(P0.05)。(5)两地区汉族西北燥证组SBP、PP、PPI、BUN、Cr、Cys-C、AD、LA、LVDd、LVDs、RA、RV、PA指标均较非西北燥证组高,同时ALBU、LVEF指标均较非西北燥证组为低,其中LA、LVDd、LVDs、RA、RV、PA、LVEF指标西北燥证组与非西北燥证组比较差异有统计学意义(P0.05)。结论:(1)随着年龄增长,乌鲁木齐、伊犁两地区汉族心血管衰老进程并非恒速。(2)30-44岁组、45-59岁组两地区汉族心血管衰老缓慢进展,乌鲁木齐汉族心血管衰老进程较伊犁汉族为快,在这两个年龄组乌鲁木齐汉族西北燥证罹患率亦较伊犁汉族为高;在四个年龄组中,60-74岁组两地区汉族心血管衰进程最快,该年龄段伊犁汉族心血管衰老进程较乌鲁木齐汉族为快,此年龄组乌鲁木齐汉族西北燥证罹患率较伊犁汉族为高,但伊犁汉族西北燥证罹患率上升幅度明显大于乌鲁木齐汉族;≥75岁组两地区汉族心血管衰老进程缓慢,再次表现为乌鲁木齐汉族心血管衰老进程较伊犁汉族略快,此年龄组伊犁汉族西北燥证罹患率较乌鲁木齐汉族为高。(3)乌鲁木齐、伊犁两地区汉族心血管衰老进展与西北燥证存在相关关系,西北燥证是影响心血管衰老进程的主要加速因素之一。
[Abstract]:Objective: To investigate the relationship between Urumqi and Yili in two areas of cardiovascular aging laws of Han and Northwest Dryness Syndrome, and provide a theoretical basis for the prevention and treatment of cardiovascular aging in Xinjiang area. Methods: from Urumqi, Yili two areas were selected in 474 cases health self evaluation of Han residents, including field investigation, laboratory test methods, echocardiography the combination of comparative differences in Urumqi, Yili two areas Han cardiovascular aging laws, correlation analysis between Northwest Dryness Syndrome and cardiovascular aging law. Results: (1) related indicators of cardiovascular aging: 1) blood pressure index: SBP, PP, PPI; 2) renal function index: BUN, Cr, Cys, C, ALBU; 3) echocardiography indicators: AD, LA, LVDd, LVDs, RA, RV, PA, LVEF. (2) in Urumqi, Yili province two related indicators of cardiovascular aging in SBP, PP, PPI, BUN, Cr, Cys, C, AD, LA, LVDd, LVDs, RA, RV, PA indexes with age increased gradually, and A LBU, LVEF were decreased gradually with aging, which can be used as a marker of cardiovascular aging index: SBP, PP, BUN, Cys, C, ALBU, LA, LVDd, LVDs, RV, LVEF. (3) in Urumqi, Yili province two NDS rate increases with age increased Urumqi Han NDS was higher than that of Han nationality in Yili (P0.05). (4) the same age group, comparison between different regions: 1) 30-44 years old group, 45-59 years old group: progress in Urumqi Han Han Yili is cardiovascular aging fast, the attack rate is also high in the Yili in two age groups in Urumqi Han Xi North dryness, of which 45-59 years old group in two areas of Northwest Dryness Syndrome rate had significant difference (P0.05); 2) 60-74 groups: the two areas are Han cardiovascular aging rapidly, in Yili Han nationality and Han nationality in Urumqi with cardiovascular aging fast, the age group of Han nationality in Urumqi of Northwest Dryness Syndrome 缃规偅鐜囪緝浼婄妬姹夋棌鐣ラ珮,浣嗕紛鐘佹眽鏃忚タ鍖楃嚗璇佺焦鎮ｇ巼涓婂崌骞呭害鏄庢樉澶т簬涔岄瞾鏈ㄩ綈姹夋棌,60-74宀佺粍涓ゅ湴鍖鸿タ鍖楃嚗璇佺焦鎮ｇ巼姣旇緝宸�寮傛棤缁熻�″�︽剰涔�(P0.05);3)鈮，

本文编号：1683610