针刺治疗腹泻型肠易激综合征临床研究的Meta分析

发布时间：2018-03-30 13:05

本文选题：腹泻型　切入点：肠易激综合征　出处：《中国针灸》2017年08期

【摘要】：目的:系统评价近5年针刺治疗腹泻型肠易激综合征的疗效性和安全性。方法:计算机检索中国知网数据库、中国维普数据库、万方数据库、PubMed、CBM、Science Direct On Site、Cochrane Library等在线数据库检索针刺治疗腹泻型肠易激综合征的随机对照试验。检索时限从2011年1月至2016年1月。由2名研究者按照改良Jadad标准对每个纳入试验进行偏倚风险和质量评估,使用RevMan 5.3软件进行Meta分析。结果:共纳入17个研究,合计1333例患者。Meta分析结果显示,针刺组或针刺加西药组对照西药组临床症状改善,总体有效率OR=3.92,95%CI[2.83~5.43](P0.01),并且漏斗图结果显示基本对称,meta分析示随访3个月复发率:OR=0.22,95%CI为[0.12~0.41](P0.01),提示针刺组随访3个月复发率小于西药组。结论:针刺治疗腹泻型肠易激综合征疗效优于常规西药治疗,可改善患者临床症状和降低复发率。
[Abstract]:Objective: to evaluate the efficacy and safety of acupuncture in treating diarrhea irritable bowel syndrome in recent 5 years. A randomized controlled trial of acupuncture in the treatment of diarrhoeal irritable bowel syndrome was conducted from January 2011 to January 2016 by a randomized controlled trial based on the online database of CBM Direct on site Cochrane Library. The search time was measured by two researchers according to the modified Jadad standard for each patient. Conduct bias risk and quality assessments in trials, Results: a total of 1333 patients were included in 17 studies. The results of meta analysis showed that the clinical symptoms of acupuncture group or acupuncture plus western medicine group were improved. The overall effective rate was 3.92c95CI [2.83v 5.43] P 0.01, and the funnel chart showed that the recurrence rate of the patients with diarrhea was 0.22995 CI = 0.120.41, which indicated that the recurrence rate of the acupuncture group was lower than that of the western medicine group. Conclusion: the acupuncture treatment of diarrhea irritable bowel syndrome is less effective than that of the western medicine group in 3 months. Conclusion: the results of funnel chart show that the recurrence rate of the patients with diarrhea irritable bowel syndrome treated by acupuncture is lower than that of the western medicine group after 3 months follow up. Conclusion: the recurrence rate of the acupuncture group is lower than the western medicine group. The effect is better than that of conventional western medicine. It can improve the clinical symptoms and reduce the recurrence rate.
【作者单位】：湖南中医药大学;
【基金】：国家自然科学青年基金课题:81303050 2014年湖南省优秀博士论文资助项目:2014-2017 湖南省中医药管理局科研计划课题:201525
【分类号】：R246.1

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