中药内服联合穴位敷贴治疗儿童哮喘缓解期肺脾气虚证的临床研究

发布时间：2018-03-31 22:26

本文选题：中医　切入点：中药内服　出处：《山西中医学院》2016年硕士论文

【摘要】：目的本研究以中药内服联合穴位敷贴治疗儿童哮喘缓解期肺脾气虚证,通过观察对相关临床症状的改善情况,以及对患儿肺功能中用力肺活量(FVC)、一秒用力呼气容积(FEV1)及呼气峰流速(PEF)的三项指标的影响,来判定临床疗效,从而为中医内外合治干预哮喘提供客观依据。方法将109例就诊于上海市中医医院属哮喘缓解期肺脾气虚证的患儿,随机分为治疗组和对照组,其中治疗组55例,对照组54例。对照组予中药内服治疗,每天2次,疗程1-3月,治疗组在对照组治疗方法基础上加用黄芩咳喘散穴位敷贴联合离子导入技术治疗,从初伏开始,每周治疗2次,6次为一个疗程,共治疗3个疗程。两组患儿在观察期间若哮喘急性发作,依据GINA治疗方案,用ICS(布地奈德混悬剂)+β2受体激动剂(可必特)治疗,必要时加用抗过敏、抗感染治疗。观察患者治疗后的中医单项症状积分、中医证候积分以及治疗后3个月、6个月观察肺功能相关指标,系统评价中药内服联合穴位敷贴对儿童哮喘缓解期肺脾气虚证患者的综合临床疗效及对肺功能的影响。结果治疗后两组的总疗效比较,治疗组和对照组分别为96.36%和90.74%,两组比较,差异具有统计学意义(P0.05),治疗组疗效优于对照组。治疗后,两组症状及中医证候积分都较治疗前减少,且治疗组优于对照组,差异具有统计学意义(P0.05),说明治疗组在改善中医症状方面有明显优势。治疗后,两组肺功能指标中FEV1、FVC、PEF三项指标在治疗后3个月和6个月均较治疗前有显著提高(P0.05),组间对比,治疗组优于对照组(P0.05)。结论中药内服联合穴位敷贴可以有效改善儿童哮喘缓解期肺脾气虚证的主要相关临床症状,且能够明显改善患儿肺功能。
[Abstract]:Objective to study the effect of traditional Chinese medicine combined with acupoint application on lung and spleen qi deficiency syndrome in children with asthma in remission period, and to observe the improvement of related clinical symptoms.The effects of three indexes on forced vital capacity (FV), forced expiratory volume (FEV _ 1) and peak expiratory flow rate (PEF) in children's lung function were also studied to evaluate the clinical efficacy and provide an objective basis for the intervention of asthma with internal and external treatment of traditional Chinese medicine.Methods 109 children with lung and spleen Qi deficiency syndrome in remission of asthma were randomly divided into treatment group (55 cases) and control group (54 cases).The control group was treated with traditional Chinese medicine orally, twice a day for 1-3 months. The treatment group was treated with Huangqin KechuanSan acupoint application combined with iontophoresis technique on the basis of the control group's treatment method. From the first volt, the treatment group was treated twice a week for 6 times as a course of treatment.There were 3 courses of treatment.During the observation period, the children in both groups were treated with GINA (budesonide suspension) 尾 _ 2 receptor agonist (Corbitt), as well as anti-allergic and anti-infective therapy according to the GINA regimen.Observe the single symptom score, TCM syndrome score and pulmonary function related indexes after 3 months and 6 months after treatment.Objective: to evaluate the comprehensive clinical effect of Chinese herbal medicine combined with acupoint application on children with asthmatic asthmatic patients with deficiency of lung temper and its effect on lung function.Results the total curative effect of the two groups after treatment was 96.36% and 90.74% respectively in the treatment group and the control group, the difference was statistically significant (P 0.05). The curative effect of the treatment group was better than that of the control group.After treatment, the symptoms and TCM syndrome scores of the two groups were decreased compared with before treatment, and the treatment group was better than the control group, the difference was statistically significant (P 0.05), which indicated that the treatment group had obvious advantages in improving TCM symptoms.After treatment, the three indexes of FEV1 FVCU PEF in the two groups were significantly higher than those before treatment 3 and 6 months after treatment, and the comparison between the two groups showed that the treatment group was better than the control group.Conclusion traditional Chinese medicine combined with acupoint application can effectively improve the main clinical symptoms of lung and spleen qi deficiency syndrome in children with asthma, and can obviously improve the lung function of children.
【学位授予单位】：山西中医学院
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R272

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