糖皮质激素依赖性皮炎的影响因素与中医体质的相关性研究

发布时间：2018-04-10 07:02

本文选题：糖皮质激素依赖性皮炎　切入点：中医体质　出处：《南京中医药大学》2016年硕士论文

【摘要】：目的：通过对临床上糖皮质激素依赖性皮炎(以下简称为激素依赖性皮炎)患者的调查及研究,初步探讨不同中医证型的患者其易患体质的分布特点,分析激素依赖性皮炎的部分影响因素与中医体质类型的相关性,研究不同体质类型发病的临床特点以及可能的演变规律,为临床辨体论治及预防激素依赖性皮炎提供新的思路。方法：本课题收录自2015年4月至2015年12月在中国医学科学院皮肤病医院门诊就诊,符合激素依赖性皮炎诊断标准的病例148份,采用流行病学中调查问卷的研究方法,判定患者的中医体质及中医证型,探讨激素依赖性皮炎患者的中医易患体质与证型间的相关性,对性别、年龄、学历、职业、月经、饮食等进行统计学分析。结果：(1)共收集148份问卷调查,单一体质计73例,兼夹体质计75例,其中阴虚质38例(26%)、阳虚质31例(21%)、气虚质29例(20%)、气郁质17例(11%)、平和质15例(10%)、特禀质7例(5%)、湿热质6例(4%)、痰湿质3例(2%)、血瘀质2例(1%)。(2)148例激素依赖性皮炎患者中,女性计135例,男性计13例。平均年龄约39岁,最小21岁,最大69岁,其中20-29岁计29例,30-39岁计67例,4049岁计41例,50岁以上计11例。(3)临床研究调查148例,风热郁肺证37例(25%),湿热蕴结证37例(25%),血虚风燥证49例(33.11%),气虚血瘀证13例(8.78%),阴虚血瘀证12例(8.11%)。不同证型与中医体质具有相关性。(4)患者的中医体质与睡眠质量具有统计学意义,与饮食偏好无统计学差异。(5)中医体质类型与月经周期有统计学差异,与经量无统计学差异。结论：(1)激素依赖性皮炎与中医体质存在一定的相关性,患者中单一体质与兼夹体质数量差不多。其中阴虚质最多,占26%,其次为阳虚质、气虚质、气郁质、平和质、特禀质、湿热质、痰湿质、血瘀质。(2)激素依赖性皮炎好发于女性,年龄多分布在30----49岁,占72.98%。29岁及以下者和50岁及以上者发病机率逐渐降低。(3)中医证型主要以风热郁肺、湿热蕴结、血虚风燥为主。风热郁肺证和湿热蕴结证的中医体质分型以阳虚质为主,也多发于气虚质、阴虚质；血虚风燥证的中医体质分型以阴虚质为主,也好发于气郁质、气虚质。(4)临床治疗激素依赖性皮炎应辩体论治,纠正偏颇体质,改善生活质量,以提高治疗及用药效果,缩短病程,减少发病。
[Abstract]:Objective: to investigate and study the patients with glucocorticoid dependent dermatitis (hereafter referred to as glucocorticoid dependent dermatitis) in order to explore the distribution characteristics of susceptible constitution of patients with different TCM syndromes.This paper analyzes the relationship between some influencing factors of hormone dependent dermatitis and TCM physique types, studies the clinical characteristics and possible evolution of different physique types, and provides a new way of thinking for clinical treatment and prevention of hormone dependent dermatitis.Methods: from April 2015 to December 2015, 148 patients who met the criteria of diagnosis of hormone dependent dermatitis in the outpatient department of dermatology hospital of Chinese Academy of Medical Sciences were studied by questionnaire in epidemiology.To determine the TCM constitution and TCM syndrome type of patients with hormone dependent dermatitis, to explore the relationship between TCM susceptible constitution and syndrome type, to analyze sex, age, educational background, occupation, menstruation, diet and so on.Results A total of 148 questionnaires were collected. There were 73 cases with a single physique and 75 cases with a physical fitness clip.There were 13 males.The average age was about 39 years old, the youngest 21 years, the oldest 69 years. Among them, 20-29 years old 29 cases, 30-39 years old 67 cases 40 49 years old 41 cases 50 years old and above 11 cases 11 cases.There were 37 cases with wind-heat depression lung syndrome, 37 cases with damp-heat accumulation syndrome, 49 cases with blood deficiency and wind dryness syndrome, 49 cases with blood deficiency and wind dryness syndrome, 13 cases with Qi deficiency and blood stasis syndrome, 13 cases with Qi deficiency and blood stasis syndrome, and 12 cases with Yin deficiency and blood stasis syndrome.The TCM constitution and sleep quality of patients with different syndromes and TCM constitution have statistical significance, and there is no statistical difference between TCM constitution type and menstrual cycle, and there is no statistical difference between TCM physique type and menstrual cycle.Conclusion there is a certain correlation between hormone dependent dermatitis and TCM constitution.Yin deficiency was the most common substance, accounting for 26%, followed by Yang deficiency, Qi deficiency, Qi stagnation, peaceful quality, intrinsic quality, dampness and heat, phlegm and dampness, blood stasis, etc.) hormone dependent dermatitis was common in women, most of which were between 30 and 49 years old.Account for 72.98.29 years old and younger and 50 years old and above the incidence rate gradually decreased. 3) the main TCM syndrome type is wind-heat stagnation lung, damp-heat accumulation knot, blood deficiency wind dryness.The types of TCM constitution of wind-heat stagnation lung syndrome and damp-heat accumulation syndrome are mainly yang deficiency, but also mainly in qi deficiency and yin deficiency; the TCM constitution classification of blood deficiency wind dryness syndrome is mainly yin deficiency, and it also tends to occur in qi stagnation.The clinical treatment of hormone dependent dermatitis should be treated by dialectics, correct the biased constitution, improve the quality of life, improve the effect of treatment and medication, shorten the course of disease and reduce the incidence.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R275.9

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