四金汤对气滞血瘀证慢性胆囊炎的临床疗效观察

发布时间：2018-04-16 03:04

本文选题：四金汤 + 慢性胆囊炎　；参考：《广西中医药大学》2017年硕士论文

【摘要】：目的:观察四金汤对气滞血瘀证慢性胆囊炎患者的临床疗效,为其治疗气滞血瘀证慢性胆囊炎提供依据。方法:将符合纳入标准的60例气滞血瘀证慢性胆囊炎患者随机分为对照组、治疗组,每组30例;对照组给予熊去氧胆酸胶囊治疗,治疗组在熊去氧胆酸胶囊治疗上加予四金汤治疗,治疗4周,观察两组治疗后的有效率、两组患者治疗前后症状积分以及胆囊彩超改善情况的变化。结果:(1)治疗组的总有效率为89.66%,对照组的总有效率75.86%,治疗组的总有效率优于对照组,差异具有统计学意义(P0.05);(2)治疗组中医证候有效率为93.10%;对照组中医证候有效率为79.31%,治疗组的中医证候有效率优于对照组,差异具有统计学意义(P0.05);(3)治疗后,治疗组的右上腹疼痛或不适感评分为1.06±0.45分,对照组的右上腹疼痛或不适感评分为1.52±0.59分,治疗组的右上腹疼痛或不适感评分低于对照组,差异具有统计学意义(P0.05);治疗后,治疗组的恶心嗳气评分为0.84±0.25分,对照组的恶心嗳气评分为1.48±0.31分,治疗组的的恶心嗳气评分低于对照组,差异具有统计学意义(P0.05);治疗后,治疗组进油腻食物后腹胀评分为1.03±0.33分,对照组进油腻食物后腹胀评分为1.87±0.42分,治疗组的进油腻食物后腹胀评分低于对照组,差异具有统计学意义(P0.05);治疗后,治疗组胆囊区压痛或叩击痛评分为0.53±0.12分,对照组胆囊区压痛或叩击痛评分为1.07±0.23分,治疗组的胆囊区压痛或叩击痛评分低于对照组,差异具有统计学意义(P0.05);治疗后,治疗组口苦咽干评分为0.54±0.20分,对照组口苦咽干评分为1.62±0.42分,治疗组的口苦咽干评分低于对照组,差异具有统计学意义(P0.05);治疗后,治疗组痛引肩背感评分为0.54±0.32分,对照组痛引肩背感评分为0.91±0.48分,治疗组的痛引肩背感评分低于对照组,差异具有统计学意义(P0.05);治疗后,治疗组纳呆食少评分为1.54±0.35分,对照组纳呆食少评分为1.88±0.61分,治疗组的纳呆食少评分低于对照组,差异具有统计学意义(P0.05);(4)治疗组胆囊彩超有效率为86.21%,对照组胆囊彩超有效率72.41%,治疗组的胆囊彩超有效率高于对照组的有效率,差异具有统计学意义(P0.05)。结论:(1)四金汤能够有效改善气滞血瘀证慢性胆囊炎患者的临床症状及体征。(2)四金汤能够明显改善气滞血瘀证慢性胆囊炎彩超影像学表现。
[Abstract]:Objective: to observe the clinical effect of Sijin decoction on chronic cholecystitis of qi stagnation and blood stasis syndrome, and to provide evidence for the treatment of chronic cholecystitis with qi stagnation and blood stasis syndrome.Methods: sixty patients with chronic cholecystitis of Qi stagnation and Blood stasis Syndrome were randomly divided into control group (n = 30) and control group (n = 30), which were treated with ursodeoxycholic acid capsule.The treatment group was treated with Sijin decoction on ursodeoxycholic acid capsule for 4 weeks. The effective rate of the two groups after treatment and the change of symptom score and the improvement of gallbladder color ultrasound before and after treatment were observed.Results the total effective rate of the treatment group was 89.66, the total effective rate of the control group was 75.86, the total effective rate of the treatment group was better than that of the control group.The effective rate of TCM syndrome in the treatment group was 93.10 and that in the control group was 79.31. The effective rate of TCM syndrome in the treatment group was better than that in the control group, and the difference was statistically significant after treatment.The scores of right epigastric pain or discomfort were 1.06 卤0.45 in the treatment group and 1.52 卤0.59 in the control group. The scores of right epigastric pain or discomfort in the treatment group were lower than those in the control group (P 0.05).The nausea belching score of the treatment group was 0.84 卤0.25, and that of the control group was 1.48 卤0.31, the score of the treatment group was lower than that of the control group (P 0.05), the abdominal distension score of the treatment group was 1.03 卤0.33 after greasy food intake.The abdominal distension score of the control group was 1.87 卤0.42 after greasy food intake, the abdominal distension score of the treatment group was lower than that of the control group, the difference was statistically significant (P 0.05), and after treatment, the gallbladder tenderness or percussion pain score was 0.53 卤0.12 in the treatment group.The score of gallbladder tenderness or percussion pain in the control group was 1.07 卤0.23, the score of gallbladder tenderness or percussion pain in the treatment group was lower than that in the control group, the difference was statistically significant (P 0.05), and after treatment, the score of dry oropharynx was 0.54 卤0.20 in the treatment group.The score of dry oropharynx in the control group was 1.62 卤0.42, and the score in the treatment group was lower than that in the control group, the difference was statistically significant (P 0.05), after the treatment, the score of the pain leading shoulder back sensation in the treatment group was 0.54 卤0.32, and that in the control group was 0.91 卤0.48, and that in the treatment group was 0.91 卤0.48, and that in the control group was 0.91 卤0.48.The scores of pain and shoulder sensation in the treatment group were lower than those in the control group, the difference was statistically significant (P 0.05), after treatment, the scores of the patients in the treatment group were 1.54 卤0.35, the scores of the patients in the control group were 1.88 卤0.61. the scores of the patients in the treatment group were lower than those in the control group, and the scores of the patients in the treatment group were lower than those in the control group.The difference was statistically significant (P 0.05)) the effective rate of color Doppler ultrasound was 86.21 in the treatment group and 72.41 in the control group. The effective rate of the treatment group was higher than that of the control group, and the difference was statistically significant.Conclusion: 1) Sijin decoction can effectively improve the clinical symptoms and signs of chronic cholecystitis with qi stagnation and blood stasis syndrome) Sijin decoction can obviously improve the imaging manifestations of chronic cholecystitis with qi stagnation and blood stasis syndrome.
【学位授予单位】：广西中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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