补肾调周法联合微刺激干预卵巢低反应不孕患者的临床研究
发布时间:2018-04-21 03:30
本文选题:补肾调周法 + 微刺激 ; 参考:《中国中西医结合杂志》2017年05期
【摘要】:目的观察补肾调周法联合微刺激对卵巢低反应(poor ovarian response,POR)不孕患者临床疗效的影响,探讨在POR患者行控制性促排卵周期中运用补肾调周法的可行性和有效性。方法将76例POR患者随机分为治疗组(38例)和对照组(38例),对照组采用微刺激方案,治疗组在对照组基础上运用补肾调周中药,疗程为3个月。比较两组肾阴虚证候改善情况、促性腺激素(Gn)天数、Gn用量、注射人绒毛膜促性腺激素(HCG)日雌二醇(E_2)水平、获卵数、MⅡ卵数、MⅡ卵受精率、优质胚胎数、优质胚胎率、周期取消率、移植日子宫内膜厚度、生化妊娠率和临床妊娠率。结果治疗组总有效率94.7%(36/38)高于对照组[76.3%(29/38)](P0.05)。治疗后治疗组获卵数、MⅡ卵数、优质胚胎数、优质胚胎率及移植日子宫内膜厚度均优于对照组(P0.05,P0.01);治疗组Gn天数、Gn用量、HCG日E_2、MⅡ卵受精率、周期取消率、生化妊娠率及临床妊娠率与对照组比较,差异均无统计学意义(P0.05)。结论补肾调周法能增加POR患者超促排卵周期的获卵数、MⅡ卵数,提高优质胚胎率,增加子宫内膜厚度,提高妊娠率。
[Abstract]:Objective to observe the effect of tonifying the kidney and regulating the week combined with micro-stimulation on the clinical efficacy of the method of tonifying the kidney and regulating the weeks of ovulation in patients with POR by using the method of tonifying the kidney and regulating the weeks of ovulation. Methods 76 patients with POR were randomly divided into treatment group (n = 38) and control group (n = 38). The improvement of kidney yin deficiency syndrome, the dosage of gonadotropin Gnn and the level of estradiol E 2 on the day of HCG injection were compared between the two groups, and the fertilization rate of M 鈪,
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