血肿消方预防动脉瘤性蛛网膜下腔出血栓塞术后继发脑积水的临床研究

发布时间：2018-04-21 16:03

本文选题：动脉瘤性蛛网膜下腔出血 + 脑积水　；参考：《河南中医药大学》2016年硕士论文

【摘要】：目的:观察动脉瘤性蛛网膜下腔出血栓塞术后患者脑积水发生情况,神经功能缺损恢复情况,中医证候积分改善情况,验证血肿消方的临床疗效,探索其防治动脉瘤性蛛网膜下腔出血继发脑积水的可能机制,为血肿消方药在防治该病脑积水的临床应用中提供中医理论依据。方法:收录符合纳入条件的动脉瘤性蛛网膜下腔出血病例30例,设为治疗组,回顾既往符合纳入标准的蛛网膜下腔出血病例30例,设为对照组。两组均采用基础治疗(应用内科药物治疗、动脉瘤栓塞术、脑脊液置换术),治疗组在基础治疗之外应用血肿消方药,疗程14天。记录患者疗程前后脑积水发生情况,神经功能缺损恢复情况,中医证候积分改善情况。结果:(1)治疗组脑积水发生率明显低于对照组(p0.05);(2)治疗前两组神经功能缺损评分无显著差异(p0.05),治疗后两组神经功能缺损评分具有显著差异(p0.05);(3)治疗前两组中医证候积分无显著差异(p0.05),治疗后两组中医证候积分具有显著差异(p0.05)。结论:血肿消方药对动脉瘤性蛛网膜下腔出血继发脑积水具有防治疗效,常规治疗措施结合血肿消方药应用可提高疗效,促进患者神经功能恢复,减少脑积水并发症,提高患者生活质量。血肿消方药能够有效预防脑积水可能与该病“瘀、热、浊、毒”的病机有关。血肿消方药临床应用安全,无不良反应及毒副作用。
[Abstract]:Objective: to observe the occurrence of hydrocephalus, the recovery of nerve function defect and the improvement of TCM syndromes in patients with aneurysm subarachnoid hemorrhage after embolization. To explore the possible mechanism of prevention and treatment of hydrocephalus secondary to aneurysm subarachnoid hemorrhage, and to provide the theoretical basis of traditional Chinese medicine for the prevention and treatment of hydrocephalus. Methods: 30 cases of aneurysm subarachnoid hemorrhage were selected as treatment group and 30 cases of subarachnoid hemorrhage were reviewed. Both groups were treated with basic treatment (internal medicine, aneurysm embolization, cerebrospinal fluid replacement), treatment group in addition to the basic treatment of hematoma treatment, the course of 14 days. The occurrence of hydrocephalus, the recovery of nerve function defect and the improvement of TCM syndromes were recorded before and after treatment. Results the incidence of hydrocephalus in the treatment group was significantly lower than that in the control group (P 0.05). There was no significant difference in the scores of nerve function defect between the two groups before and after treatment, but there was a significant difference in the scores of nerve function defect between the two groups after treatment. There was no significant difference in the scores of TCM syndrome between the two groups after treatment, and there was a significant difference between the two groups in the score of TCM syndromes. Conclusion: the treatment of hydrocephalus secondary to aneurysm subarachnoid hemorrhage with the prescription of hematoma elimination can improve the curative effect, promote the recovery of nerve function and reduce the complications of hydrocephalus. Improve the quality of life of patients. Hematoma elimination prescription can effectively prevent hydrocephalus may be related to the disease "stasis, heat, turbid, toxic" pathogenesis. Hematoma elimination prescription is safe in clinical application and has no side effects and side effects.
【学位授予单位】：河南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.7

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