自拟化痰通络汤治疗稳定型心绞痛（痰瘀互阻证）的临床观察

发布时间：2018-04-22 08:21

本文选题：稳定型心绞痛 + 冠心病　；参考：《黑龙江中医药大学》2017年硕士论文

【摘要】：目的:通过对比观察自拟化痰通络汤治疗冠心病稳定型心绞痛(痰瘀互阻证)患者治疗前后西雅图心绞痛量表积分、中医证候积分、心绞痛发作情况、硝酸甘油用量情况的变化,探讨其临床疗效。方法:本临床观察共纳入符合入组标准的患者40例,均来自2016年3月-2016年12月在黑龙江中医药大学附属第一医院心内科门诊就诊的患者。采用治疗前后自身对照的方法,患者入组后予自拟化痰通络汤150ml/次,2次/日,用药疗程4周。记录并统计对比患者治疗前后的西雅图心绞痛量表、中医证候积分、心绞痛发作情况、硝酸甘油用量情况的变化。结果:1.治疗后患者西雅图心绞痛量表中躯体活动受限程度、心绞痛稳定状态、心绞痛发作情况、治疗满意程度均较治疗前明显改善,差异具有统计学意义(P0.05)。2.治疗后患者中医证候积分较治疗前明显下降,差异有统计学意义(P0.05)。3.治疗后患者心绞痛积分较治疗前显著降低,差异有统计学意义(P0.05)。4.治疗后患者硝酸甘油停减率为84.21%,疗效显著。结论:1.自拟化痰通络汤能有效改善冠心病稳定型心绞痛(痰瘀互阻证)患者的躯体活动受限程度、心绞痛稳定状态、心绞痛发作情况、降低硝酸甘油的使用率,并提高患者对疾病治疗的满意程度。2.自拟化痰通络汤能有效改善冠心病稳定型心绞痛(痰瘀互阻证)患者的中医证候表现。
[Abstract]:Objective: to observe the score of Seattle angina scale, TCM syndrome score and angina pectoris attack before and after treatment of stable angina pectoris (phlegm and blood stasis mutual obstruction syndrome) patients with coronary heart disease treated with Huatan Tongluo decoction. The change of nitroglycerin dosage and its clinical effect were discussed. Methods: a total of 40 patients, all from March 2016 to December 2016, were enrolled in the clinical observation. They were admitted to the Department of Cardiology of the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine from March 2016 to December 2016. Before and after treatment, the patients were treated with 150ml/ twice a day, and the course of treatment was 4 weeks. The changes of Seattle angina scale, TCM syndrome score, angina pectoris attack and nitroglycerin dosage before and after treatment were recorded and compared statistically. The result is 1: 1. After treatment, the degree of restricted somatic activity, stable state of angina pectoris, angina pectoris attack and satisfactory degree of treatment in the patients with Seattle angina pectoris scale were significantly improved compared with those before treatment, and the difference was statistically significant (P 0.05). After treatment, the score of TCM syndromes in patients was significantly lower than that before treatment, and the difference was statistically significant (P 0.05). 3. After treatment, the score of angina pectoris was significantly lower than that before treatment, and the difference was statistically significant (P 0.05. 4). After treatment, the reduction rate of nitroglycerin was 84.21 and the curative effect was remarkable. Conclusion 1. Self-made Huatan Tongluo decoction can effectively improve the degree of restricted physical activity, stable state of angina pectoris, angina pectoris attack and decrease the utilization rate of nitroglycerin in patients with stable angina pectoris of coronary heart disease (phlegm and blood stasis mutual obstruction syndrome). And to improve the patient's satisfaction with the treatment of the disease. 2. Self-made Huatan Tongluo decoction can effectively improve the TCM syndromes of patients with stable angina pectoris of coronary heart disease (phlegm and blood stasis mutual obstruction syndrome).
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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