中医治疗糖尿病皮肤瘙痒症用药规律研究

发布时间：2018-04-22 15:33

本文选题：糖尿病皮肤瘙痒症 + 中医治疗　；参考：《山东中医药大学》2016年硕士论文

【摘要】：目的:探寻糖尿病皮肤瘙痒症现代文献中的中医用药规律,以期为临床治疗及研究提供可靠参考。方法:收集1995年~2015年相关期刊论文中有关中医药治疗糖尿病皮肤瘙痒症的文献,从药物应用角度出发,深入研究与其相关的内服中药规律。运用Excel2003软件建立相关数据库,以药物为变量,方剂中出现的药物赋值为1,未出现者赋值为0。应用频数分析寻找高频药物、药类、药性,通过聚类分析得到关系密切的药对和聚类方,探讨药物配伍规律。结果:根据本研究的纳入标准与排除标准共筛选出符合条件的文献65篇,方剂76首,涉及治疗本病的药物120味,药物使用总频数为850次。其中药物使用频数超过20次的有13味,累计频数为393次,累计频率为46.23%,是治疗糖尿病皮肤瘙痒症的核心药物。在治疗糖尿病皮肤瘙痒症的药物中,药类分析结果显示清热药和补虚药使用频数最高,频数分别为223次、219次。药物四气中以寒性药物为主;药物五味以甘、苦、辛为主;药物归经以肝、脾、肾、心、肺为主。结论:糖尿病皮肤瘙痒症的发生本虚标实、虚实夹杂,本虚以血虚、气阴两虚为主,标实以热邪、风邪、瘀血为主,临床用药时应攻补兼施。
[Abstract]:Objective: to explore the rule of traditional Chinese medicine (TCM) in modern literature on diabetic pruritus and to provide a reliable reference for clinical treatment and research. Methods: the literatures on the treatment of diabetic pruritus with traditional Chinese medicine (TCM) were collected from 1995 to 2015 in the full text database of Chinese Journal of China. From the point of view of drug application, the regularity of internal administration of traditional Chinese medicine (TCM) was deeply studied. The Excel2003 software was used to establish the related database. Taking the drug as the variable, the drug assignment in the prescription was 1, and the value in the non-occurrence was 0. The frequency analysis was used to search for high frequency drugs, drugs and drugs. By cluster analysis, the closely related drug pairs and prescriptions were obtained, and the law of drug compatibility was discussed. Results: a total of 65 articles and 76 prescriptions were selected according to the inclusion criteria and exclusion criteria of this study, which involved 120 kinds of drugs for the treatment of this disease. The total frequency of drug use was 850 times. Among them, 13 drugs were used more than 20 times, the cumulative frequency was 393, and the cumulative frequency was 46.23. It is the core drug for treating diabetic skin pruritus. In the treatment of diabetic pruritus, the results of drug category analysis showed that the use frequency of heat-clearing drugs and tonifying drugs were the highest, which were 223 times and 219 times respectively. The drugs are mainly cold drugs; the five flavors of drugs are sweet, bitter and Xin; the drugs belong to liver, spleen, kidney, heart and lung, and the drugs are mainly composed of liver, spleen, kidney, heart and lung. Conclusion: the occurrence of diabetes skin pruritus is based on the deficiency of blood, deficiency of qi and yin, heat evil, wind evil and blood stasis.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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