桑杏玉女煎治疗慢性咳嗽（胃阴不足，燥邪干肺）的临床研究

发布时间：2018-04-22 17:53

本文选题：桑杏玉女煎 + 慢性咳嗽　；参考：《长春中医药大学》2016年硕士论文

【摘要】：目的:本课题为自拟方桑杏玉女煎治疗慢性咳嗽(胃阴不足、燥邪干肺)的临床观察研究,通过与对照药物复方甲氧那明胶囊做对比,验证本方对于慢性咳嗽(胃阴不足、燥邪干肺)病人的是否有疗效。探讨慢性咳嗽的发病机理,拓展本方的临床应用范围。方法:按照纳入排除标准,选取符合慢性咳嗽(胃阴不足、燥邪干肺)诊断标准的患者60例,将入组的患者随机分为治疗组和对照组,每组各30例。其中对照组30例给予复方甲氧那明胶囊口服,治疗组30例口服中药汤剂桑杏玉女煎(包含中药桑叶、杏仁、北沙参、浙贝母、栀子、牛膝、知母等),每组患者服药14天。观察两组病人治疗前后对慢性咳嗽主症和兼证的症状改善、中医证候积分等疗效指标的变化。结果:实验结果显示,在治疗组30例患者中,治愈7例(23.3%),显效12例(40%),有效9例(30%),总有效率92.3%,对照组治愈1例(3.3%),显效3例(10%),有效18例(60%),总有效率73.3%,在症状改善方面,经统计学分析,除了对于主症咳嗽的改善两组无显著性差异,对于兼症痰少而粘、口燥咽干、烦热干渴、口鼻干燥、大便干燥的治疗,治疗组疗效明显优于对照组。综合总有效率及对于中医症状的改善,治疗组疗效明显优于对照组。结论:桑杏玉女煎对于慢性咳嗽(胃阴不足、燥邪干肺证)患者有着良好的治疗效果,并且无明显不良反应,具有临床推广应用价值。
[Abstract]:Objective: To study the clinical study of Fang sang apricot Yidu Decoction in the treatment of chronic cough (deficiency of stomach yin, dryness and dry lung), through comparison with the contrast drug Compound Methoxyphenamine Capsules, to verify the efficacy of the prescription for chronic cough (deficiency of stomach, dry and dry lung), explore the pathogenesis of chronic cough and expand the clinical effect of this prescription. Method: according to the exclusion criteria, 60 patients with chronic cough (deficiency of stomach yin, dryness and dry lung) were selected and divided into the treatment group and the control group randomly, 30 cases in each group, of which 30 cases in the control group were given Compound Methoxyphenamine Capsules oral, 30 cases of oral Chinese medicine decoction of mulberry apricot yam decoction. Including Chinese medicine mulberry leaves, almonds, Radix apricot, Fritillaria thunbergii, gardenia, gardenia, Achyranthes, Anemarrhena, and so on, each group of patients took 14 days to take medicine. Observe the changes of the symptoms of chronic cough and concurrently before and after treatment of two groups of patients and TCM syndrome score. Results: the results showed that in the 30 patients of the treatment group, 7 cases (23.3%) were cured and 12 cases were markedly effective (40). The effective 9 cases (30%), the total effective rate 92.3%, the control group cured 1 cases (3.3%), 3 cases (10%), effective 18 cases (60%), the total effective 73.3%, in the symptom improvement, in addition to the improvement of the main symptoms of cough in the two groups of no significant difference, to concurrent phlegm less and sticky, dry throat, irritated thirst, nose dry, dry stool, dry stool treatment, The curative effect of the treatment group was obviously better than that of the control group. The comprehensive total effective rate and the improvement of TCM symptoms were better than the control group. Conclusion: Sang Xing Yidu decoction had good therapeutic effect on the patients with chronic cough (deficiency of stomach yin, dryness and dry lung syndrome), and there was no obvious adverse reaction, which had clinical application value.

【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R256.11

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